CCR7 anticorps

N° du produit ABIN2664346

L’anticorps anti-CCR7 Monoclonal Rat est utilisé pour la détection de CCR7 dans des échantillons de Souris. Il a été validé pour WB, IHC, IF, ICFC et CyTOF.

Aperçu rapide pour CCR7 anticorps (ABIN2664346)

Antigène: CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp CCR7 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Intracellular Flow Cytometry (ICFC), Cytometry by Time of Flight (CyTOF)

Clone: 4B12

Détail du produit anti-CCR7 anticorps

Purification: The antibody was purified by affinity chromatography.

Isotype: IgG2a kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C.

Détails sur CCR7

Antigène: CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))

Autre désignation: CD197

Sujet: CD197 is also known as C-C chemokine receptor 7 (CCR7) or EBI-1. CCR7 is a G-coupled rhodopsin-like member of the GPCR superfamily with a predicted molecular weight of 43 kD that is expressed on hematopoietic stem cells, most naive T cells, some memory T cells, B subset, and mature dendritic cells. CCR7 is a receptor for the chemokines CCL19 (MIP3 beta) and SLC (6CKine, Exodus-2, TCA-4, CCL21) that plays a role in thymocytes development, T cell adhesion at intestinal sites, the homeostatic recirculation of memory T cells, and chemotaxis.

Pathways: Regulation of Actin Filament Polymerization, Positive Regulation of Immune Effector Process