Neuropilin 1 anticorps

N° du produit ABIN2664540

Cet anticorps Souris Monoclonal détecte spécifiquement Neuropilin 1 dans ELISA (Capture) et ELISPOT (Capture). Il présente une réactivité envers Humain.

Aperçu rapide pour Neuropilin 1 anticorps (ABIN2664540)

Antigène: Neuropilin 1 (NRP1)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Neuropilin 1 est non-conjugé

Application: ELISA (Capture), ELISpot (Capture) (ELISPOT (Capture))

Clone: 12C2

Détail du produit anti-Neuropilin 1 anticorps

Purification: The antibody was purified by affinity chromatography.

Isotype: IgG2a kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C.

Détails sur Neuropilin 1

Antigène: Neuropilin 1 (NRP1)

Autre désignation: CD304

Sujet: CD304, also known as neuropilin-1, BDCA-4 and VEGF165R, is a 140 kD type I transmembrane protein. Its extracellular region contains two CUB, two FV/FVIII, and one MAM domain, a soluble isoform is produced by alternative mRNA splicing. CD304 is involved in angiogenesis, neural development, and tumor metastasis. It is expressed by plasmacytoid dendritic cells, thymocytes, neurons, endothelium, and a subset of TFH cells. CD304 is also expressed in several carcinomas, and a high expression of this molecule in prostate cancer correlates with a poor prognosis.

Pathways: Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals