CD41, CD61 anticorps

N° du produit ABIN2664684

Cet anticorps Souris Monoclonal détecte spécifiquement CD41, CD61 dans FACS. Il présente une réactivité envers Humain.

Aperçu rapide pour CD41, CD61 anticorps (ABIN2664684)

Antigène: CD41, CD61 (CD41,CD61)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD41, CD61 est non-conjugé

Application: Flow Cytometry (FACS)

Clone: PAC-1

Détail du produit anti-CD41, CD61 anticorps

Purification: The antibody was purified by affinity chromatography.

Isotype: IgM kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C.

Détails sur CD41, CD61

Antigène: CD41, CD61 (CD41,CD61)

Autre désignation: CD41/CD61

Sujet: The gpIIb/IIIa complex, also known as integrin αIIbβ3, is expressed by megakaryocytes and platelets. It undergoes conformational changes upon activation by substances, such as ADP, thrombin, and TXA2, which subsequently reveals a ligand binding site that is specific for fibrinogen, von Willebrand factor (vWF), fibronectin, and vitronectin. This conformational change is crucial for platelet-platelet adhesion. Ligand bound gpIIb/IIIa complex promotes platelet aggregation. This complex plays an important role in hemostasis and is a target for developing therapeutic antibodies in immune thrombocytopenia.