EPO anticorps
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- Antigène Voir toutes EPO Anticorps
- EPO (Erythropoietin (EPO))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp EPO est non-conjugé
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Application
- Flow Cytometry (FACS)
- Purification
- The antibody was purified by affinity chromatography.
- Clone
- M0312E3
- Isotype
- IgG2b kappa
- Top Product
- Discover our top product EPO Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Stockage commentaire
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- Antigène
- EPO (Erythropoietin (EPO))
- Autre désignation
- EPO (EPO Produits)
- Synonymes
- anticorps EPO, anticorps EP, anticorps MVCD2, anticorps erythropoietin, anticorps erythropoietin S homeolog, anticorps erythropoietin a, anticorps EPO, anticorps epo, anticorps epo.S, anticorps Epo, anticorps epoa
- Classe de substances
- Hormone
- Sujet
- EPO is the major regulator of differentiation, proliferation, and survival of erythroid progenitors. Hypoxia induces erythropoiesis which causes cells to produce hypoxia inducible factor (HIF) that is directly involved in EPO expression. HIF-Prolyl hydroxylase (HIF-PH) is a sensor of levels of iron, oxygen, and metabolic activity. High levels of HIF protein induce EPO production in the kidneys and liver, and mobilize iron to support erythropoiesis. EPO has been used in the treatment of anemia associated with a number of conditions, such as chronic kidney disease, cancer patients on chemotherapy, and antiviral HIV therapy.
- Pathways
- Signalistation JAK/STAT, Hormone Activity, Negative Regulation of intrinsic apoptotic Signaling, Negative Regulation of Transporter Activity
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