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EPO anticorps

EPO Reactivité: Souris FACS Hôte: Rat Monoclonal M029F6 unconjugated
N° du produit ABIN2664956
  • Antigène Voir toutes EPO Anticorps
    EPO (Erythropoietin (EPO))
    Reactivité
    • 128
    • 31
    • 23
    • 7
    • 6
    • 4
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    Souris
    Hôte
    • 112
    • 49
    • 2
    • 1
    • 1
    Rat
    Clonalité
    • 114
    • 51
    Monoclonal
    Conjugué
    • 89
    • 18
    • 14
    • 9
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp EPO est non-conjugé
    Application
    • 121
    • 78
    • 48
    • 41
    • 29
    • 14
    • 14
    • 13
    • 13
    • 13
    • 8
    • 8
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Purification
    The antibody was purified by affinity chromatography.
    Clone
    M029F6
    Isotype
    IgG2b
    Top Product
    Discover our top product EPO Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Antigène
    EPO (Erythropoietin (EPO))
    Autre désignation
    EPO (EPO Produits)
    Synonymes
    anticorps EPO, anticorps EP, anticorps MVCD2, anticorps erythropoietin, anticorps erythropoietin S homeolog, anticorps erythropoietin a, anticorps EPO, anticorps epo, anticorps epo.S, anticorps Epo, anticorps epoa
    Classe de substances
    Hormone
    Sujet
    EPO is a glycoprotein that is glycosylated up to 40-60 % , which causes its molecular weight to vary from 30-34 kD depending on the carbohydrate percentage. Hypoxia induces erythropoiesis, and hypoxia inducible factor (HIF) is directly involved in EPO expression. HIF-Prolyl hydroxylase (HIF-PH) is a sensor of levels of iron, oxygen, and metabolic activity. High levels of HIF protein induces EPO production in the kidneys and liver, and mobilizes iron to support erythropoiesis. EPO has been used in the treatment of anemia associated with chronic kidney disease, treatment of cancer patients on chemotherapy, and antiviral HIV therapy.
    Pathways
    Signalistation JAK/STAT, Hormone Activity, Negative Regulation of intrinsic apoptotic Signaling, Negative Regulation of Transporter Activity
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