EPO anticorps
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- Antigène Voir toutes EPO Anticorps
- EPO (Erythropoietin (EPO))
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Reactivité
- Souris
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Hôte
- Rat
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp EPO est non-conjugé
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Application
- Flow Cytometry (FACS)
- Purification
- The antibody was purified by affinity chromatography.
- Clone
- M029F6
- Isotype
- IgG2b
- Top Product
- Discover our top product EPO Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Stockage commentaire
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- Antigène
- EPO (Erythropoietin (EPO))
- Autre désignation
- EPO (EPO Produits)
- Synonymes
- anticorps EPO, anticorps EP, anticorps MVCD2, anticorps erythropoietin, anticorps erythropoietin S homeolog, anticorps erythropoietin a, anticorps EPO, anticorps epo, anticorps epo.S, anticorps Epo, anticorps epoa
- Classe de substances
- Hormone
- Sujet
- EPO is a glycoprotein that is glycosylated up to 40-60 % , which causes its molecular weight to vary from 30-34 kD depending on the carbohydrate percentage. Hypoxia induces erythropoiesis, and hypoxia inducible factor (HIF) is directly involved in EPO expression. HIF-Prolyl hydroxylase (HIF-PH) is a sensor of levels of iron, oxygen, and metabolic activity. High levels of HIF protein induces EPO production in the kidneys and liver, and mobilizes iron to support erythropoiesis. EPO has been used in the treatment of anemia associated with chronic kidney disease, treatment of cancer patients on chemotherapy, and antiviral HIV therapy.
- Pathways
- Signalistation JAK/STAT, Hormone Activity, Negative Regulation of intrinsic apoptotic Signaling, Negative Regulation of Transporter Activity
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