IL-34 anticorps

N° du produit ABIN2665167

Cet anticorps Rat Monoclonal détecte spécifiquement IL-34 dans IP. Il présente une réactivité envers Souris.

Aperçu rapide pour IL-34 anticorps (ABIN2665167)

Antigène: IL-34 (IL34) (Interleukin 34 (IL34))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp IL-34 est non-conjugé

Application: Immunoprecipitation (IP)

Clone: C051-77

Détail du produit anti-IL-34 anticorps

Purification: The antibody was purified by affinity chromatography.

Isotype: IgG2c

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C.

Détails sur IL-34

Antigène: IL-34 (IL34) (Interleukin 34 (IL34))

Autre désignation: IL-34

Sujet: IL-34 is a glycoprotein that plays important roles in the proliferation, survival, and differentiation of monocytes and macrophages. IL-34 is expressed in the heart, brain, lung, liver, kidney, thymus, spleen, and other organs. It specifically binds to CD115/M-CSF receptor (CSF-1 receptor or c-Fms) and activates ERK1/2 phosphorylation. The function of IL-34 overlaps with CSF-1 to regulate myeloid lineage development. IL-34 also promotes inflammatory processes and regulates osteoclast proliferation, differentiation, and bone reabsorption.

Pathways: Signalisation RTK