Galectin 3 anticorps (AA 151-251)

N° du produit ABIN2665254

L’anticorps Souris Monoclonal anti-Galectin 3 a été validé pour IP. Il convient pour détecter Galectin 3 dans des échantillons de Humain et Souris.

Aperçu rapide pour Galectin 3 anticorps (AA 151-251) (ABIN2665254)

Antigène: Galectin 3 (LGALS3)

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Galectin 3 est non-conjugé

Application: Immunoprecipitation (IP)

Clone: Gal397

Détail du produit anti-Galectin 3 anticorps

Épitope: AA 151-251

Purification: The antibody was purified by affinity chromatography.

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C.

Détails sur Galectin 3

Antigène: Galectin 3 (LGALS3)

Autre désignation: Mac-2

Classe de substances: Chemical

Sujet: Galectin-3 (galactose-specific lectin 3) is a 30-32 kD glycoprotein, also know as Mac-2, Gal-3, RL-29, galactose-specific lectin 3, CBP-35, L-34, and εBP. It is a member of animal β-galactoside-binding protein family that is expressed in cell nucleus, cytoplasm, plasma membrane, or extracellular matrix by variety of tumor cells, monocytes/macrophages, epithelial cells, Kupffer cells, and dendritic cells. Galectin-3 contains carbohydrate recognition domains and binds to β-galactoside residues bearing glycoproteins, such as as IgE, IgA, galactose, casein kinase I, laminin, mucin, LAMPs, and CD66. Galectin-3 is an adhesion molecule and plays an important role in regulation of cell proliferation, differentiation and tumor cell metastasis. Galectin-3 structurely possesses NWGR motif that is conserved in BH-1 domain of BCL-2 family and functions as an anti-apoptotic molecule.

Pathways: Signalisation RTK