CD40 Ligand anticorps

N° du produit ABIN2665953

Cet anticorps anti-CD40 Ligand est un anticorps Souris Monoclonal détectant CD40 Ligand dans FACS. Adapté pour Humain.

Aperçu rapide pour CD40 Ligand anticorps (ABIN2665953)

Antigène: CD40 Ligand (CD40LG)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD40 Ligand est non-conjugé

Application: Flow Cytometry (FACS)

Clone: 24-31

Détail du produit anti-CD40 Ligand anticorps

Marque: Ultra-LEAF™

Réactivité croisée: Cynomolgus, Macaque rhésus

Purification: The Ultra-LEAF™ (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.

Stérilité: 0.2 μm filtered

niveau d'endotoxine:

Endotoxin level is <0.01 EU/μg of the protein (<0.001 ng/μg of the protein) as determined by the LAL test.

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Agent conservateur: Azide free

Conseil sur la manipulation: This Ultra-LEAF™ solution contains no preservative, handle under aseptic conditions

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C.

Détails sur CD40 Ligand

Antigène: CD40 Ligand (CD40LG)

Autre désignation: CD154

Sujet: CD154 (CD40 ligand) is also known as CD40L, gp39, TRAP and T-BAM. CD40 ligand is a 32-39 kD type II transmembrane glycoprotein. It is a member of the TNF superfamily and is expressed on activated T cells. It has been reported to be important for B cell costimulation following binding of its receptor, CD40. Additionally, binding of CD40L to CD40 on B cells promotes the secretion of immunoglobulin and Ig isotype switching. CD40L is also involved in the regulation of cytokine production by T cells.

Pathways: Signalisation NF-kappaB, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints