CD16 anticorps

N° du produit ABIN2665954

L’anticorps anti-CD16 Monoclonal Souris est utilisé pour la détection de CD16 dans des échantillons de Humain. Il a été validé pour FACS et WB.

Aperçu rapide pour CD16 anticorps (ABIN2665954)

Antigène: CD16

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD16 est non-conjugé

Application: Flow Cytometry (FACS), Western Blotting (WB)

Clone: 3G8

Détail du produit anti-CD16 anticorps

Réactivité croisée: Chimpanzé, Babouin, Cynomolgus, Macaque rhésus, Marmoset, Capuchin Monkey, Pigtailed Macaque, Sooty mangabey (Cercocebus atys), Squirrel Monkey (Saimiri spec.), Saguinus oedipus

Attributs du produit: This product is produced with low endotoxin and is supplied azide free.

Purification: The Ultra-LEAF™ (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.

Stérilité: 0.2 μm filtered

niveau d'endotoxine:

Endotoxin level is <0.01 EU/μg of the protein (<0.001 ng/μg of the protein) as determined by the LAL test.

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Agent conservateur: Azide free

Conseil sur la manipulation: This Ultra-LEAF™ solution contains no preservative, handle under aseptic conditions

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C.

Détails sur CD16

Antigène: CD16

Autre désignation: CD16

Sujet: CD16 is known as low affinity IgG receptor III (FcγRIII). It is expressed as two distinct forms (CD16a and CD16b). CD16a (FcγRIIIA) is a 50-65 kD polypeptide-anchored transmembrane protein. It is expressed on the surface of NK cells, activated monocytes, macrophages, and placental trophoblasts in humans. CD16b (FcγRIIIB) is a 48 kD glycosylphosphatidylinositol (GPI)-anchored protein. Its extracellular domain is over 95 % homologous to that of CD16a, and it is expressed specifically on neutrophils. CD16 binds aggregated IgG or IgG-antigen complex which functions in NK cell activation, phagocytosis, and antibody-dependent cell-mediated cytotoxicity (ADCC).

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process