Acetylated Lysine anticorps (acetylated)
Aperçu rapide pour Acetylated Lysine anticorps (acetylated) (ABIN2666081)
Antigène
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- acetylated
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Purification
- The antibody was purified by affinity chromatography.
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Isotype
- IgG2b kappa
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 0.5 mg/mL
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Buffer
- phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- Upon receipt, store between 2°C and 8°C.
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- Acetylated Lysine
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Classe de substances
- Chemical
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Sujet
- Proteins are reversibly and dynamically acetylated on the ε-amino group of lysine by acetyltransferases and deacetylated by deacetylases. This post-translational modification can regulate protein function (interactions with other proteins and DNA binding). Histones and transcription factors (PCAF, p53, p300, etc) appear to be the major targets of acetyltransferases. Acetylation is usually associated with chromatin remodeling and transcriptional activation, although in some cases (telomeres) it is associated with gene silencing. The 15G10 antibody recognizes acetylated lysine residues on proteins.
Antigène
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