KAP1 anticorps

N° du produit ABIN2666087

Cet anticorps anti-KAP1 est un anticorps Souris Monoclonal détectant KAP1 dans BCA. Adapté pour Humain.

Aperçu rapide pour KAP1 anticorps (ABIN2666087)

Antigène: KAP1 (TRIM28) (Tripartite Motif Containing 28 (TRIM28))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp KAP1 est non-conjugé

Application: Biochemical Assay (BCA)

Clone: 20A1

Détail du produit anti-KAP1 anticorps

Purification: The antibody was purified by affinity chromatography.

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide at 0.5 mg/mL.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Upon receipt, store between 2°C and 8°C.

Détails sur KAP1

Antigène: KAP1 (TRIM28) (Tripartite Motif Containing 28 (TRIM28))

Autre désignation: TIF1beta KAP-1

Sujet: TIFβ (transcription intermediary factor 1-beta) is an 88 kD member of the tripartite motif family. This protein contains three zinc binding domains, a RING domain, a B-box type 1 and type 2 domain, and a coiled-coil region. TIFβ is found in the nucleus and associates with specific chromatin regions. This protein forms a complex with KRAB-domain transcription factors and recruits setdbl to histone 3 to increase KRAB-mediated transcriptional repression. TIF1β has been reported to interact with setdbl and cbx3 proteins. Studies using knockout mice reveal the important function of TIF1β in regulating genomic imprinting, T cell activation, and T cell tolerance.

Pathways: Signalisation Hedgehog, Positive Regulation of Response to DNA Damage Stimulus