IRF3 anticorps
-
- Antigène Voir toutes IRF3 Anticorps
- IRF3 (Interferon Regulatory Factor 3 (IRF3))
-
Reactivité
- Humain, Souris
-
Hôte
- Souris
-
Clonalité
- Monoclonal
-
Conjugué
- Cet anticorp IRF3 est non-conjugé
-
Application
- Biochemical Assay (BCA)
- Purification
- Affinity purified
- Clone
- 12A4A35
- Isotype
- IgG2b kappa
- Top Product
- Discover our top product IRF3 Anticorps primaire
-
anti-Interferon Regulatory Factor 3 (IRF3) (pSer396) antibody
IRF3 Reactivité: Humain, Souris, Rat, Singe WB, ELISA, IHC (p), ICC, IF (cc), IF (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated
anti-Interferon Regulatory Factor 3 (IRF3) antibodyIRF3 Reactivité: Humain, Souris, Rat WB, IHC, IF Hôte: Lapin Polyclonal unconjugated
anti-Interferon Regulatory Factor 3 (IRF3) (AA 1-260) antibodyIRF3 Reactivité: Humain WB, IHC, IF, ChIP Hôte: Lapin Polyclonal unconjugated
anti-Interferon Regulatory Factor 3 (IRF3) (AA 1-452) antibodyIRF3 Reactivité: Humain WB, ELISA, IF, IP Hôte: Souris Monoclonal 3C8 unconjugated
anti-Interferon Regulatory Factor 3 (IRF3) (AA 1-360) antibodyIRF3 Reactivité: Humain WB, IHC, IP, ICC Hôte: Lapin Polyclonal unconjugated
anti-Interferon Regulatory Factor 3 (IRF3) (AA 51-150) antibodyIRF3 Reactivité: Humain, Souris, Rat, Singe, Boeuf (Vache) WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated
anti-Interferon Regulatory Factor 3 (IRF3) (C-Term) antibodyIRF3 Reactivité: Humain WB, ELISA, IHC, IF, ICC Hôte: Lapin Polyclonal unconjugated
anti-Interferon Regulatory Factor 3 (IRF3) (pSer386) antibodyIRF3 Reactivité: Humain, Rat WB, ELISA, IHC, IF, ICC Hôte: Lapin Polyclonal unconjugated
anti-Interferon Regulatory Factor 3 (IRF3) (AA 1268-1341) antibodyIRF3 Reactivité: Humain WB, ELISA, IHC Hôte: Lapin Polyclonal unconjugated
anti-Interferon Regulatory Factor 3 (IRF3) (AA 1-452) antibodyIRF3 Reactivité: Humain WB, ELISA, IHC, IF Hôte: Lapin Polyclonal unconjugated
-
- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Concentration
- 0.5 mg/mL
- Buffer
- phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Stockage commentaire
- Upon receipt, store undiluted between 2°C and 8°C.
-
- Antigène
- IRF3 (Interferon Regulatory Factor 3 (IRF3))
- Autre désignation
- IRF3 (IRF3 Produits)
- Synonymes
- anticorps irf3, anticorps IRF3, anticorps C920001K05Rik, anticorps IRF-3, anticorps interferon regulatory factor 3, anticorps interferon regulatory factor 7, anticorps irf3, anticorps IRF3, anticorps irf-3, anticorps Irf3, anticorps IRF7
- Sujet
- IRF-3 is a member of the interferon regulatory transcription factor (IRF) family. It mediates interferon-stimulated response element (ISRE) promoter activation and functions as a molecular switch for antiviral activity. DsRNA generated during the course of a viral infection leads to IRF-3 phosphorylation on the C-terminal serine/threonine cluster. This induces a conformational change, leading to its dimerization, nuclear localization and association with CREB protein binding to dsRNA-activated factor 1, a complex which activates the transcription of genes under control of ISRE. The phosphorylated IRF-3 is under negative regulation by ubiquitin-mediated degradation. Research indicates that it plays a critical role in stimulated TLR-mediated IL-27 p28 gene expression.
- Pathways
- Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Toll-Like Receptors Cascades
-
