RAG2 anticorps

N° du produit ABIN2666293

L’anticorps Souris Monoclonal anti-RAG2 a été validé pour WB. Il convient pour détecter RAG2 dans des échantillons de Humain et Souris.

Aperçu rapide pour RAG2 anticorps (ABIN2666293)

Antigène: RAG2 (Recombination Activating Gene 2 (RAG2))

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp RAG2 est non-conjugé

Application: Western Blotting (WB)

Clone: 3G4A26

Détail du produit anti-RAG2 anticorps

Purification: Affinity purified.

Isotype: IgG2b kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: phosphate-buffered solution, pH 7.2, containing 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Upon receipt, store undiluted between 2°C and 8°C.

Détails sur RAG2

Antigène: RAG2 (Recombination Activating Gene 2 (RAG2))

Autre désignation: RAG2

Sujet: During T cell and B cell development, RAG2 works together with RAG1 to induce DNA rearrangement and assembly of antigen receptor coding segments. Defects in RAG2 gene lead to the complete lack of mature T and B lymphocytes and result in severe combined immunodeficiency (SCID). RAG2 also functions in chromosome binding through its unique plant homeodomain (PHD). Sequestration of recombination signal sequences (RSS) within the nucleosome by RAG2 prevents access by the recombinase complex.

Pathways: Chromatin Binding, Production of Molecular Mediator of Immune Response