ATIC anticorps

N° du produit ABIN2666312

Cet anticorps anti-ATIC est un anticorps Souris Monoclonal détectant ATIC dans BCA. Adapté pour Humain, Souris, Rat, Drosophila melanogaster et Grenouille.

Aperçu rapide pour ATIC anticorps (ABIN2666312)

Antigène: ATIC (5-Aminoimidazole-4-Carboxamide Ribonucleotide Formyltransferase/IMP Cyclohydrolase (ATIC))

Reactivité: Humain, Souris, Rat, Drosophila melanogaster, Grenouille

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ATIC est non-conjugé

Application: Biochemical Assay (BCA)

Clone: F38P7H9

Détail du produit anti-ATIC anticorps

Purification: The antibody was purified by affinity chromatography.

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide at 0.5 mg/mL.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Upon receipt, store undiluted between 2°C and 8°C.

Détails sur ATIC

Antigène: ATIC (5-Aminoimidazole-4-Carboxamide Ribonucleotide Formyltransferase/IMP Cyclohydrolase (ATIC))

Autre désignation: ATIC

Sujet: ATIC (AICAR transformylase/IMP cyclohydrolase) belongs to the purH family, expressed in the cytoplasm, predicted molecular weight approximately 65 kD. ATIC catalyzes the penultimate and final steps in the de novo purine nucleotide biosynthesis pathway. ATIC acts as a bifunctional enzyme catalyze the formation of FAICAR and IMP. AICA-ribosiduria is a recently discovered inherited metabolic disease caused by a defect in final steps of purine de novo biosynthesis. Clone F38P7H9 has been shown to be useful for western blotting and immunohistochemistry of human, mouse, rat, frog and fruit fly ATIC.