BID anticorps

N° du produit ABIN2666317

Détail du produit anti-BID anticorps

Antigène: BID (BH3 Interacting Domain Death Agonist (BID))

Reactivité: Humain

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp BID est non-conjugé

Application: Flow Cytometry (FACS)

Purification: The antibody was purified by affinity chromatography.

Clone: 1H11

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: phosphate-buffered solution, pH 7.2, 0.09 % Sodium azide.

Stock: 4 °C

Stockage commentaire: Upon receipt, store undiluted between 2°C and 8°C.

Détails sur BID

Antigène: BID (BH3 Interacting Domain Death Agonist (BID))

Autre désignation: BID (BID Produits)

Synonymes: anticorps FP497, anticorps 2700049M22Rik, anticorps AI875481, anticorps AU022477, anticorps BID, anticorps bid, anticorps si:ch211-238n5.6, anticorps fp497, anticorps xbid, anticorps DKFZp469E066, anticorps BH3 interacting domain death agonist, anticorps BH3 interacting domain death agonist S homeolog, anticorps BID, anticorps Bid, anticorps bida, anticorps bid.S, anticorps bid

Sujet: BID, a BH3 interacting domain death agonist is a member of the Bcl-2/Bcl-xL family. BID can form a heterodimer with either agonist BAX or antagonist Bcl-2. It is a mediator of mitochondrial damage induced by Caspase-8 (CASP8). After the cleavage by CASP8, the COOH-terminal part translocates to mitochondria and induces cytochrome c release, which in turn activates downstream caspases. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined.

Pathways: Apoptose, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity