GPR177/WLS anticorps

N° du produit ABIN2666414

Détail du produit anti-GPR177/WLS anticorps

Antigène: GPR177/WLS (WLS) (Wntless Homolog (WLS))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp GPR177/WLS est non-conjugé

Application: Flow Cytometry (FACS)

Clone: YJ5

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Upon receipt, store undiluted between 2°C and 8°C.

Détails sur GPR177/WLS

Antigène: GPR177/WLS (WLS) (Wntless Homolog (WLS))

Autre désignation: Wntless (WLS Produits)

Synonymes: anticorps C1orf139, anticorps EVI, anticorps GPR177, anticorps MRP, anticorps mig-14, anticorps 5031439A09Rik, anticorps AI173978, anticorps AI987742, anticorps Gpr177, anticorps gpr117, anticorps gpr177, anticorps sb:cb610, anticorps wu:fb36d04, anticorps wu:fb44d10, anticorps wu:fb50c06, anticorps zgc:64091, anticorps CG6210, anticorps Dmel\\CG6210, anticorps Evi, anticorps Evi/Wls, anticorps Srt, anticorps Wls, anticorps Wls/Evi, anticorps evi, anticorps srt, anticorps wls/evi, anticorps wntless Wnt ligand secretion mediator, anticorps wntless homolog (Drosophila), anticorps wntless, anticorps WLS, anticorps Wls, anticorps wls

Sujet: Wnt signaling plays important roles in embryonic development and cancer formation. Wntless (GPR177) is a putative G-protein coupled receptor that regulates Wnt's trafficking and secretion. It can regulate the expression, subcellular location, binding, and organelle-specific association of Wnt proteins. In mammals, Wntless is mainly expressed in submucosa, muscle, ganglia, and nerve cells of the large intestines. Overexpression of Wntless may activate the NF-κB signaling pathway in cancer cells.

Pathways: Signalisation WNT