HIPK2 anticorps (AA 898-1051)

N° du produit ABIN2668288

Il existe 1 publication pour ce produit. L’anticorps anti-HIPK2 Monoclonal Souris est utilisé pour la détection de HIPK2 dans des échantillons de Humain. Il a été validé pour WB, IHC, IP, ICC et IF.

Aperçu rapide pour HIPK2 anticorps (AA 898-1051) (ABIN2668288)

Antigène: HIPK2 (Homeodomain Interacting Protein Kinase 2 (HIPK2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp HIPK2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunofluorescence (IF)

Clone: 3E9

Détail du produit anti-HIPK2 anticorps

Épitope: AA 898-1051

Fonction: HIPK2 antibody (mAb) (Clone 3E9)

Purification: Protein G Chromatography

Immunogène: This HIPK2 antibody was raised against a recombinant protein including amino acids 898-1051 of mouse HIPK2.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1 μg/μL

Buffer: Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Stock: -20 °C

Stockage commentaire: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Date de péremption: 24 months

Références pour anticorps anti-HIPK2 (ABIN2668288)

Isono, Nemoto, Li, Takada, Suzuki, Katsuki, Nakagawara, Koseki: "Overlapping roles for homeodomain-interacting protein kinases hipk1 and hipk2 in the mediation of cell growth in response to morphogenetic and genotoxic signals." dans: Molecular and cellular biology, Vol. 26, Issue 7, pp. 2758-71, (2006) (PubMed).

Détails sur HIPK2

Antigène: HIPK2 (Homeodomain Interacting Protein Kinase 2 (HIPK2))

Autre désignation: HIPK2

Sujet: HIPK2 (Homeodomain Interacting Protein Kinase 2) is a serine/threonine kinase present in the nucleus that interacts with homeodomain transcription factors and acts as a co-repressor of transcription. It inhibits cell growth, as well as promotes apoptosis through the phosphorylation and subsequent degradation of the anti-apoptotic factor CTBP1. HIPK2 also phosphorylates CBX4 upon DNA damage and promotes its E3 SUMO-protein ligase activity.

Poids moléculaire: 130 kDa

ID gène: 28996

NCBI Accession: NP_034563

Pathways: Cycle Cellulaire