HDAC4 anticorps (AA 194-209)

N° du produit ABIN2668313

Cet anticorps anti-HDAC4 est un anticorps Lapin Polyclonal détectant HDAC4 dans WB, ChIP et ChIP-seq. Adapté pour Humain et Souris. Ce Primary Antibody a été cité dans 9+ publications.

Aperçu rapide pour HDAC4 anticorps (AA 194-209) (ABIN2668313)

Antigène: HDAC4 (Histone Deacetylase 4 (HDAC4))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HDAC4 est non-conjugé

Application: Western Blotting (WB), Chromatin Immunoprecipitation (ChIP), ChIP DNA-Sequencing (ChIP-seq)

Détail du produit anti-HDAC4 anticorps

Épitope: AA 194-209

Purification: Affinity Purified

Immunogène: This HDAC4 antibody was raised against a synthetic peptide corresponding to amino acid residues 194-209 of human HDAC4.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 μg/μL

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation:

Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Stock: -80 °C

Stockage commentaire: Antibodies in solution can be stored at -80 °C for 2 years.

Date de péremption: 6 months

Références pour anticorps anti-HDAC4 (ABIN2668313)

Liu, Gu, Feng, Yang, Zhu, Lu, Qi: "Both HDAC5 and HDAC6 are required for the proliferation and metastasis of melanoma cells." dans: Journal of translational medicine, Vol. 14, pp. 7, (2016) (PubMed).

Isaacs, Antony, Dalrymple, Brennen, Gerber, Hammers, Wissing, Kachhap, Luo, Xing, Björk, Olsson, Björk, Leanderson: "Tasquinimod Is an Allosteric Modulator of HDAC4 survival signaling within the compromised cancer microenvironment." dans: Cancer research, Vol. 73, Issue 4, pp. 1386-99, (2013) (PubMed).

Keedy, Archin, Gates, Espeseth, Hazuda, Margolis: "A limited group of class I histone deacetylases acts to repress human immunodeficiency virus type 1 expression." dans: Journal of virology, Vol. 83, Issue 10, pp. 4749-56, (2009) (PubMed).

Mottet, Bellahcène, Pirotte, Waltregny, Deroanne, Lamour, Lidereau, Castronovo: "Histone deacetylase 7 silencing alters endothelial cell migration, a key step in angiogenesis." dans: Circulation research, Vol. 101, Issue 12, pp. 1237-46, (2007) (PubMed).

Sayeed, Konduri, Liu, Bansal, Li, Das: "Estrogen receptor alpha inhibits p53-mediated transcriptional repression: implications for the regulation of apoptosis." dans: Cancer research, Vol. 67, Issue 16, pp. 7746-55, (2007) (PubMed).

Testoni, Mantovani: "Mechanisms of transcriptional repression of cell-cycle G2/M promoters by p63." dans: Nucleic acids research, Vol. 34, Issue 3, pp. 928-38, (2006) (PubMed).

Basile, Mantovani, Imbriano: "DNA damage promotes histone deacetylase 4 nuclear localization and repression of G2/M promoters, via p53 C-terminal lysines." dans: The Journal of biological chemistry, Vol. 281, Issue 4, pp. 2347-57, (2006) (PubMed).

Imbriano, Gurtner, Cocchiarella, Di Agostino, Basile, Gostissa, Dobbelstein, Del Sal, Piaggio, Mantovani: "Direct p53 transcriptional repression: in vivo analysis of CCAAT-containing G2/M promoters." dans: Molecular and cellular biology, Vol. 25, Issue 9, pp. 3737-51, (2005) (PubMed).

Caretti, Salsi, Vecchi, Imbriano, Mantovani: "Dynamic recruitment of NF-Y and histone acetyltransferases on cell-cycle promoters." dans: The Journal of biological chemistry, Vol. 278, Issue 33, pp. 30435-40, (2003) (PubMed).

Détails sur HDAC4

Antigène: HDAC4 (Histone Deacetylase 4 (HDAC4))

Autre désignation: HDAC4

Poids moléculaire: 140 kDa

ID gène: 9759

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process