Histone 3 anticorps (H3K122me1)

N° du produit ABIN2668462

Il existe 1 publication pour ce produit. L’anticorps anti-Histone 3 Polyclonal Lapin est utilisé pour la détection de Histone 3 dans des échantillons de Humain. Il a été validé pour WB et DB.

Aperçu rapide pour Histone 3 anticorps (H3K122me1) (ABIN2668462)

Antigène: Histone 3 (H3) (Histone H3 (H3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Histone 3 est non-conjugé

Application: Western Blotting (WB), Dot Blot (DB)

Détail du produit anti-Histone 3 anticorps

Épitope: H3K122me1

Fonction: Histone H3K122me1 antibody (pAb)

Purification: Affinity Purified

Immunogène: This Histone H3 monomethyl Lys122 antibody was raised against a peptide containing monomethyl-lysine 122 of human histone H3.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:250 - 1:1,000 dilution

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Stock: -20 °C

Stockage commentaire: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Date de péremption: 24 months

Références pour anticorps anti-Histone 3 (ABIN2668462)

Ivanauskiene, Delbarre, McGhie, Küntziger, Wong, Collas: "The PML-associated protein DEK regulates the balance of H3.3 loading on chromatin and is important for telomere integrity." dans: Genome research, Vol. 24, Issue 10, pp. 1584-94, (2014) (PubMed).

Détails sur Histone 3

Antigène: Histone 3 (H3) (Histone H3 (H3))

Autre désignation: Histone H3

Sujet: Histone H3 is one of the core components of the nucleosome. The nucleosome is the smallest subunit of chromatin and consists of 147 base pairs of DNA wrapped around an octamer of core histone proteins (two each of Histone H2A, Histone H2B, Histone H3 and Histone H4). Chromatin is subject to a variety of chemical modifications, including post-translational modifications of the histone proteins and the methylation of cytosine residues in the DNA. Reported histone modifications include acetylation, methylation, phosphorylation, ubiquitylation, glycosylation, ADP-ribosylation, carbonylation and SUMOylation, these modifications play a major role in regulating gene expression. The methylation of histones can occur on two different residues: arginine or lysine. Histone methylation can be associated with transcriptional activation or repression, depending on the methylated residue.

Poids moléculaire: 17 kDa

ID gène: 3020

NCBI Accession: NP_003522