Rpb1 CTD anticorps (Tyr1)

N° du produit ABIN2668519

Détail du produit anti-Rpb1 CTD anticorps

Antigène: Rpb1 CTD (RNA Polymerase II CTD)

Épitope: Tyr1

Reactivité: Humain

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp Rpb1 CTD est non-conjugé

Application: Western Blotting (WB), Chromatin Immunoprecipitation (ChIP), Immunoprecipitation (IP)

Purification: Protein G Chromatography

Immunogène: This antibody was raised against a synthetic peptide containing the RNA Pol II heptad repeat consensus sequence phosphorylated at tyrosine 1.

Clone: 3D12

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1 μg/μL

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation:

Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Stock: -20 °C

Stockage commentaire: Antibodies in solution can be stored at -20 °C for 2 years.

Date de péremption: 6 months

Références pour anticorps anti-Rpb1 CTD (ABIN2668519)

Harlen, Trotta, Smith, Mosaheb, Fuchs, Churchman: "Comprehensive RNA Polymerase II Interactomes Reveal Distinct and Varied Roles for Each Phospho-CTD Residue." dans: Cell reports, Vol. 15, Issue 10, pp. 2147-2158, (2016) (PubMed).

Laitem, Zaborowska, Isa, Kufs, Dienstbier, Murphy: "CDK9 inhibitors define elongation checkpoints at both ends of RNA polymerase II-transcribed genes." dans: Nature structural & molecular biology, Vol. 22, Issue 5, pp. 396-403, (2015) (PubMed).

Zaborowska, Baumli, Laitem, OReilly, Thomas, OHare, Murphy: "Herpes Simplex Virus 1 (HSV-1) ICP22 protein directly interacts with cyclin-dependent kinase (CDK)9 to inhibit RNA polymerase II transcription elongation." dans: PLoS ONE, Vol. 9, Issue 9, pp. e107654, (2014) (PubMed).

Mayer, Heidemann, Lidschreiber, Schreieck, Sun, Hintermair, Kremmer, Eick, Cramer: "CTD tyrosine phosphorylation impairs termination factor recruitment to RNA polymerase II." dans: Science (New York, N.Y.), Vol. 336, Issue 6089, pp. 1723-5, (2012) (PubMed).

Détails sur Rpb1 CTD

Antigène: Rpb1 CTD (RNA Polymerase II CTD)

Autre désignation: RNA Pol II CTD (Rpb1 CTD Produits)

Synonymes: anticorps 5, anticorps 8WG16, anticorps CG1554, anticorps CTD, anticorps Dmel\\CG1554, anticorps H5, anticorps II, anticorps L5, anticorps POL, anticorps Pol II, anticorps Pol II CTD, anticorps Pol II Ser5P, anticorps Pol II0[ser2], anticorps Pol II0[ser5], anticorps Pol II[ser2], anticorps Pol IIa, anticorps Pol IIo, anticorps Pol IIo[Ser2], anticorps Pol IIo[ser2], anticorps Pol IIo[ser5], anticorps Pol-IIa, anticorps PolII, anticorps PolIIo, anticorps RNA Pol II, anticorps RNA Pol II CTD, anticorps RNA PolI 215, anticorps RNA PolII, anticorps RNA pol II, anticorps RNA pol IIo, anticorps RNA polII, anticorps RNAP, anticorps RNAP II, anticorps RNAP II LS, anticorps RNAPII, anticorps RNAPII0, anticorps RNApol2, anticorps RNApolII, anticorps RPB1, anticorps RPII215, anticorps RpII, anticorps Rpb1, anticorps Rpll215, anticorps Ubl, anticorps dRPB1, anticorps dRpb1, anticorps l(1)10Ca, anticorps l(1)DC912, anticorps l(1)DF912, anticorps l(1)G0040, anticorps l(1)L5, anticorps pol II, anticorps polII, anticorps RNA polymerase II 215kD subunit, anticorps RpII215

Poids moléculaire: 210 kDa

ID gène: 5430