PBX1 anticorps
Aperçu rapide pour PBX1 anticorps (ABIN2668628)
Antigène
Voir toutes PBX1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- PBX1b antibody (mAb) (Clone CT 41.1)
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Purification
- Protein G Chromatography
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Immunogène
- This PBX1b antibody was raised against a recombinant protein corresponding to amino acids 319 - 347 of human PBX1b.
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Isotype
- IgG1 kappa
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 1 μg/μL
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Buffer
- Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage
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Stock
- -20 °C
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Stockage commentaire
- Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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Date de péremption
- 24 months
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: "Identification of Pbx1, a potential oncogene, as a Notch3 target gene in ovarian cancer." dans: Cancer research, Vol. 68, Issue 21, pp. 8852-60, (2008) (PubMed).
: "A Pbx1-dependent genetic and transcriptional network regulates spleen ontogeny." dans: Development (Cambridge, England), Vol. 132, Issue 13, pp. 3113-26, (2005) (PubMed).
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- PBX1 (Pre-B-Cell Leukemia Homeobox Protein 1 (PBX1))
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Autre désignation
- PBX1b
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Sujet
- PBX proteins are a family of TALE-class transcription factors that associate with a subset of Hox proteins, enhancing their DNA binding affinities and specificities. PBX proteins also heterodimerize with the Meis/Prep subfamily of to form trimeric complexes with Hox proteins at specific DNA sites. Amino acids 348-430 are absent in isoform PBX1b.
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Poids moléculaire
- 40 kDa
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ID gène
- 5087
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NCBI Accession
- NP_001191890
Antigène
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