IRF3 anticorps (AA 306-312)

N° du produit ABIN2668684

Il existe 1 publication pour ce produit. L’anticorps anti-IRF3 Polyclonal Lapin est utilisé pour la détection de IRF3 dans des échantillons de Humain. Il a été validé pour WB et ChIP.

Aperçu rapide pour IRF3 anticorps (AA 306-312) (ABIN2668684)

Antigène: IRF3 (Interferon Regulatory Factor 3 (IRF3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IRF3 est non-conjugé

Application: Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)

Détail du produit anti-IRF3 anticorps

Épitope: AA 306-312

Fonction: IRF-3 antibody (pAb)

Purification: Unpurified

Immunogène: This IRF-3 antibody was raised against a peptide corresponding to residues 306-312 of human IRF-3.

Information d'application

Indications d'application: WB: 1:1,000 - 1:2,000 dilution

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Rabbit serum containing 30 % glycerol and 0.035 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Stock: -20 °C

Stockage commentaire: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Date de péremption: 24 months

Références pour anticorps anti-IRF3 (ABIN2668684)

Goriely, Molle, Nguyen, Albarani, Haddou, Lin, De Wit, Flamand, Willems, Goldman: "Interferon regulatory factor 3 is involved in Toll-like receptor 4 (TLR4)- and TLR3-induced IL-12p35 gene activation." dans: Blood, Vol. 107, Issue 3, pp. 1078-84, (2006) (PubMed).

Détails sur IRF3

Antigène: IRF3 (Interferon Regulatory Factor 3 (IRF3))

Autre désignation: IRF-3

Sujet: IRF-3 (Interferon regulatory factor 3 or IRF3) is a member of the IRF family of transcription factors that include IRF-1, IRF-6 and IRF-7. IRF-3 that has been phosphorylated at serine/threonine forms a complex with CREBBP and translocates to the nucleus to activate transcription of interferon-induced genes.

Poids moléculaire: 50 kDa

ID gène: 3661

NCBI Accession: NP_001562

Pathways: Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Toll-Like Receptors Cascades