STAT5 A/B anticorps (pTyr694, pTyr699)

N° du produit ABIN2668940

Cité dans 1 publication. Cet anticorps anti-STAT5 A/B Polyclonal Lapin (ABIN2668940) détecte spécifiquement STAT5 A/B dans WB et DB. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour STAT5 A/B anticorps (pTyr694, pTyr699) (ABIN2668940)

Antigène: STAT5 A/B

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp STAT5 A/B est non-conjugé

Application: Western Blotting (WB), Dot Blot (DB)

Détail du produit anti-STAT5 A/B anticorps

Épitope: pTyr694, pTyr699

Fonction: STAT5A/B phospho Tyr694/Tyr699 antibody (pAb)

Purification: Affinity Purified

Immunogène: This STAT5A/B phospho Tyr694/Tyr699 antibody was raised against a peptide containing phospho Tyr694 of human STAT5A. Human STAT5B shares the identical sequence surrounding Tyr699.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500 - 1:2,000 dilution

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Stock: -20 °C

Stockage commentaire: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Date de péremption: 24 months

Références pour anticorps anti-STAT5 A/B (ABIN2668940)

Basu, Wu, Kopchick: "Targeting growth hormone receptor in human melanoma cells attenuates tumor progression and epithelial mesenchymal transition via suppression of multiple oncogenic pathways." dans: Oncotarget, Vol. 8, Issue 13, pp. 21579-21598, (2017) (PubMed).

Détails sur STAT5 A/B

Antigène: STAT5 A/B

Autre désignation: STAT5A/B

Sujet: STAT5A/B (signal transducer and activator of transcription 5) is a member of the STAT family of transcription factors. STATs undergo serine and tyrosine phosphorylation in response to growth factor or cytokine signaling. This phosphorylation results in dimerization and translocation of STAT proteins to the nucleus. The STAT5 protein is expressed in most cell types and is activated by multiple cytokines and growth factors including: IFNA1, IL-10, IL-6, IL-11, IL-12, IL-2, EGF, among others. Other members of the STAT family include STAT1a, STAT2, STAT3, STAT4, STAT5A, STAT5B and STAT6.

Poids moléculaire: 92 kDa

ID gène: 6776