N6-Methyladenosine anticorps

N° du produit ABIN2668972

L’anticorps anti-N6-Methyladenosine Polyclonal Lapin est utilisé pour la détection de N6-Methyladenosine. Il a été validé pour DB.

Aperçu rapide pour N6-Methyladenosine anticorps (ABIN2668972)

Antigène: N6-Methyladenosine

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Dot Blot (DB)

Détail du produit

Fonction: N6-Methyladenosine (m6A) antibody (pAb)

Purification: Protein A Chromatography

Immunogène: This antibody was raised against 6-Methyladenosine conjugated to KLH.

Isotype: IgG

Information d'application

Indications d'application: DB: 1 - 2 μg/mL dilution For N6-Methyladenosine (m6A), we also offer AbFlex N6-Methyladenosine (m6A) Recombinant Antibody (rAb). For details, see Catalog No. 91261.

Restrictions: For Research Use only

Stockage

Concentration: 1 μg/μL

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Stock: -20 °C

Stockage commentaire: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Date de péremption: 24 months

Détail du antigène

Antigène: N6-Methyladenosine

Classe de substances: Chemical

Sujet: N6-Methyladenosine (m6A) ) is an RNA modification on the N-6 position of adenosine. This modification has been found to be abundant in the 3' UTR and stop codons of mammalian mRNA. m6A is associated with miRNA binding sites suggesting a potential role in epigenetic gene regulation. FTO and ALKBH are demethylases for 6-methyladenosine while a multiprotein complex that includes METTL3 functions as the methyltransferase. Recent findings revealed that m6A is also present on metazoan DNA, suggesting a genuine epigenetic role for this modification in the context of DNA as well.