N6-Methyladenosine anticorps

N° du produit ABIN6972397

Détail du produit

Antigène: N6-Methyladenosine

Reactivité: Humain, Saccharomyces cerevisiae

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Inconjugué

Application: Dot Blot (DB), Immunoprecipitation (IP)

Attributs du produit: N6-Methyladenosine (m6A) ) is an RNA modification on the N-6 position of adenosine. This modification has been found to be abundant in the 3' UTR and stop codons of mammalian mRNA. m6A is associated with miRNA binding sites suggesting a potential role in epigenetic gene regulation. FTO and ALKBH are demethylases for 6-methyladenosine while a multiprotein complex that includes METTL3 functions as the methyltransferase. Recent findings revealed that m6A is also present on metazoan DNA, suggesting a genuine epigenetic role for this modification in the context of DNA as well. N6-Methyladenosine (m6A) antibody (mAb) (Clone 17-3-4-1) was raised in a Mouse host. It has been validated for use in Dot blot and Immunoprecipitation, it has been shown to react with Budding Yeast and Human samples, but the sequence is not species specific so it should react with a wide range of sample types.

Purification: Protein A Chromatography

Immunogène: This antibody was raised against 6-Methyladenosine conjugated to BSA.

Clone: 17-3-4-1

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Détail du antigène

Antigène: N6-Methyladenosine

Autre désignation: N6-Methyladenosine (m6A)