Ubiquitin anticorps

N° du produit ABIN2668990

Il existe 1 publication pour ce produit. L’anticorps anti-Ubiquitin Monoclonal Souris est utilisé pour la détection de Ubiquitin dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour Ubiquitin anticorps (ABIN2668990)

Antigène: Ubiquitin (Ub)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Ubiquitin est non-conjugé

Application: Western Blotting (WB)

Clone: P4D1

Détail du produit anti-Ubiquitin anticorps

Fonction: Ubiquitin antibody (mAb) (Clone P4D1)

Purification: Protein A Chromatography

Immunogène: This Ubiquitin antibody was raised against purified bovine ubiquitin.

Isotype: IgG

Information d'application

Indications d'application: WB For additional information, please see the original publication for the generation of this clone: Kahana, A., and Gottschling, D.E., Mol. Cell. Biol. 19: 6608-6620, 1999. This antibody is also available as an AbFlex engineered recombinant antibody. For details on the corresponding AbFlex Recombinant Antibody, see Catalog No. 91257.

Restrictions: For Research Use only

Stockage

Concentration: 1 μg/μL

Buffer: PBS, 30 % glycerol and 0.035 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Stock: -20 °C

Stockage commentaire: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Date de péremption: 24 months

Références pour anticorps anti-Ubiquitin (ABIN2668990)

Kahana, Gottschling: "DOT4 links silencing and cell growth in Saccharomyces cerevisiae." dans: Molecular and cellular biology, Vol. 19, Issue 10, pp. 6608-20, (2000) (PubMed).

Détails sur Ubiquitin

Antigène: Ubiquitin (Ub)

Autre désignation: Ubiquitin

Sujet: Ubiquitin is an important signaling protein that is catalytically added to proteins on lysine residues to modify their function. Addition of multiple ubiquitin proteins in a string (poly-ubiquitylation) to proteins signals their destruction by the proteasome. Mono-ubiquitylation of proteins has a much different effect, more in keeping with post-translational modification of proteins by phosphorylation or acetylation. Mono-ubiquitylation is part of a number of signal transduction pathways, including those involving histone proteins and transcriptional regulation.

Pathways: Mitotic G1-G1/S Phases, Ubiquitin Proteasome Pathway