BACE1 anticorps (AA 112-324)
Aperçu rapide pour BACE1 anticorps (AA 112-324) (ABIN2682977)
Antigène
Voir toutes BACE1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 112-324
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Fonction
- BACE1 Antibody
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Purification
- Purified antibody
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Immunogène
- Purified recombinant fragment of human BACE1 (AA: 112-324) expressed in E. Coli.
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Isotype
- IgG1
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Indications d'application
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- BACE1 (Beta-secretase 1 (BACE1))
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Autre désignation
- BACE1
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Sujet
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Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the protein encoded by this gene. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Multiple transcript variants encoding different isoforms have been described for this gene.
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Poids moléculaire
- 55.7 kDa
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ID gène
- 23621
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UniProt
- P56817
Antigène
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