Menin anticorps (AA 392-554)
Aperçu rapide pour Menin anticorps (AA 392-554) (ABIN2682998)
Antigène
Voir toutes Menin (MEN1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 392-554
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Fonction
- MEN1 Antibody
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Purification
- Purified antibody
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Immunogène
- Purified recombinant fragment of human MEN1 (AA: 392-554) expressed in E. Coli.
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Isotype
- IgG1
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Indications d'application
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ELISA: 1/10000
FCM: 1/200 - 1/400
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Menin (MEN1) (Multiple Endocrine Neoplasia 1 (MEN1))
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Autre désignation
- MEN1
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Sujet
- This gene encodes menin, a putative tumor suppressor associated with a syndrome known as multiple endocrine neoplasia type 1. In vitro studies have shown menin is localized to the nucleus, possesses two functional nuclear localization signals, and inhibits transcriptional activation by JunD, however, the function of this protein is not known. Two messages have been detected on northern blots but the larger message has not been characterized. Alternative splicing results in multiple transcript variants.
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Poids moléculaire
- 68 kDa
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ID gène
- 4221
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UniProt
- O00255
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Pathways
- Chromatin Binding, Positive Regulation of Endopeptidase Activity
Antigène
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