TIE1 anticorps (AA 385-607)

N° du produit ABIN2683015

L’anticorps anti-TIE1 Monoclonal Souris est utilisé pour la détection de TIE1 dans des échantillons de Humain. Il a été validé pour ELISA et IHC.

Aperçu rapide pour TIE1 anticorps (AA 385-607) (ABIN2683015)

Antigène: TIE1 (tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TIE1 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Clone: 8D12D2

Détail du produit anti-TIE1 anticorps

Épitope: AA 385-607

Fonction: TIE1 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human TIE1 (AA: 385-607) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur TIE1

Antigène: TIE1 (tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1))

Autre désignation: TIE1

Sujet: This gene encodes a member of the tyrosine protein kinase family. The encoded protein plays a critical role in angiogenesis and blood vessel stability by inhibiting angiopoietin 1 signaling through the endothelial receptor tyrosine kinase Tie2. Ectodomain cleavage of the encoded protein relieves inhibition of Tie2 and is mediated by multiple factors including vascular endothelial growth factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Poids moléculaire: 125 kDa

UniProt: P35590

Pathways: Signalisation RTK