IL2 Receptor beta anticorps

N° du produit ABIN2688930

Détail du produit anti-IL2 Receptor beta anticorps

Antigène: IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp IL2 Receptor beta est non-conjugé

Application: Flow Cytometry (FACS), Immunoprecipitation (IP)

Marque: BD Pharmingen™

Attributs du produit: The 5H4 antibody reacts with mouse CD122, the 75-85kD β chain of the mouse IL-2 receptor, but does not block IL-2 binding to the IL-2 receptor. The IL-2R β chain is constitutively expressed on a subset of CD8+ spleen T cells, on NK cells, and at lower levels on a small population of resting B cells. IL-2R β chain expression is up-regulated by IL-2. The immunogen used to generate this hybridoma was rat myeloma cells transfected with a truncated IL-2R β cDNA.

BD Pharmingen™ Purified Rat Anti-Mouse CD122 - Purified - Clone 5H4 - Isotype Rat IgG2a, κ - Reactivity Ms - 0.5 mg

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Immunogène: Rat myeloma cells transfected with a truncated IL-2R beta cDNA

Clone: 5H4

Isotype: IgG2a kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store undiluted at 4°C.

Références pour anticorps anti-IL2 Receptor beta (ABIN2688930)

Malek, Furse, Fleming, Fadell, He: "Biochemical identity and characterization of the mouse interleukin-2 receptor beta and gamma c subunits." dans: Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, Vol. 15, Issue 5, pp. 447-54, (1995) (PubMed).

Furse, Malek et al.: "Selection of internalization-deficient cells by interleukin-2-Pseudomonas exotoxin chimeric protein: the cytoplasmic domain of the interleukin-2 receptor beta chain does not contribute to ..." dans: European journal of immunology, Vol. 23, Issue 12, pp. 3181-8, (1994) (PubMed).

Détails sur IL2 Receptor beta

Antigène: IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))

Autre désignation: CD122 (IL2RB Produits)

Synonymes: anticorps IL2RB, anticorps il-2rb, anticorps CD122, anticorps IL15RB, anticorps P70-75, anticorps IL2RBC, anticorps IL-15Rbeta, anticorps IL15Rbeta, anticorps Il-2/15Rbeta, anticorps Il-2Rbeta, anticorps p70, anticorps interleukin 2 receptor subunit beta, anticorps interleukin-2 receptor subunit beta, anticorps interleukin 2 receptor, beta, anticorps interleukin 2 receptor, beta chain, anticorps IL2RB, anticorps LOC510185, anticorps il2rb, anticorps Il2rb

Sujet: Synonyms: IL-2 and IL-15 Receptor β chain, P75

Pathways: Signalistation JAK/STAT, Growth Factor Binding