Cadherin 5 anticorps

N° du produit ABIN2688978

L’anticorps Rat Monoclonal anti-Cadherin 5 a été validé pour IP, FACS, IHC (fro) et BR. Il convient pour détecter Cadherin 5 dans des échantillons de Souris. Il y a 3+ publications disponibles.

Aperçu rapide pour Cadherin 5 anticorps (ABIN2688978)

Antigène: Cadherin 5 (CDH5)

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp Cadherin 5 est non-conjugé

Application: Immunoprecipitation (IP), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Blocking Reagent (BR)

Clone: 11D4-1

Détail du produit anti-Cadherin 5 anticorps

Marque: BD Pharmingen™

Attributs du produit: The 11D4.1 antibody reacts with mouse VE-cadherin, a member of the cadherin family. VE-cadherin is an endothelial cell-specific, homophilic adhesion molecule. It is concentrated at interendothelial cells contacts and is thought to be involved in the maintenance of cell layer integrity. In vitro and in vivo studies indicate that the 11D.4 mAb interferes with VE-cadherin-mediated intercellular adhesion. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature.

BD Pharmingen™ Purified Rat Anti-Mouse CD144 - Purified - Clone 11D4.1 - Isotype Rat IgG2a, κ - Reactivity Ms - 0.5 mg

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Immunogène: Mouse VE-Cadherin-Ig Fusion Protein

Isotype: IgG2a kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store undiluted at 4°C.

Références pour anticorps anti-Cadherin 5 (ABIN2688978)

Gotsch, Borges, Bosse, Böggemeyer, Simon, Mossmann, Vestweber: "VE-cadherin antibody accelerates neutrophil recruitment in vivo." dans: Journal of cell science, Vol. 110 ( Pt 5), pp. 583-8, (1997) (PubMed).

Breier, Breviario, Caveda, Berthier, Schnürch, Gotsch, Vestweber, Risau, Dejana: "Molecular cloning and expression of murine vascular endothelial-cadherin in early stage development of cardiovascular system." dans: Blood, Vol. 87, Issue 2, pp. 630-41, (1996) (PubMed).

Lampugnani, Resnati, Raiteri, Pigott, Pisacane, Houen, Ruco, Dejana: "A novel endothelial-specific membrane protein is a marker of cell-cell contacts." dans: The Journal of cell biology, Vol. 118, Issue 6, pp. 1511-22, (1992) (PubMed).

Détails sur Cadherin 5

Antigène: Cadherin 5 (CDH5)

Autre désignation: CD144

Sujet: Synonyms: VE-Cadherin, Cadherin-5

Pathways: Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2