BST1 anticorps

N° du produit ABIN2688997

Détail du produit anti-BST1 anticorps

Antigène: BST1 (Bone Marrow Stromal Cell Antigen 1 (BST1))

Reactivité: Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp BST1 est non-conjugé

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunofluorescence (IF), Immunoaffinity Chromatography (IAC)

Marque: BD Pharmingen™

Attributs du produit: The BP-3 antibody reacts with CD157, also known as the BP-3 alloantigen or Bone marrow STromal cell antigen-1 (BST-1), found in a variety of common laboratory strains of mice (AKR, BALB/c, CBA/N, C3H/HeJ, C57BL/6, DBA/2, NZB, C.B-17, SJL and Swiss, but not A/J). CD157 is a differentially glycosylated GPI-linked cell-surface glycoprotein with a core protein of 32 kDa and differing patterns of glycosylation in different types of cells. It is a member, along with CD38, of a family of genetically-related ectoenzymes. The BP-3 alloantigen is expressed on the B lineage from the earliest detectable progenitors to circulating immature B lymphocytes, on immature thymocytes up to the expression of the T-cell receptor, on circulating neutrophils, peritoneal macrophages, on subpopulations of stromal cells in peripheral lymphoid organs (but not in bone marrow or thymus), on intestinal epithelial cells, and in the lumen of kidney-collecting tubules. The distribution of CD157 antigen on leukocytes and stromal cells of lymphoid organs suggests that it may be involved in leukocyte-stroma interactions which support the development, migration, and/or responses of leukocyte populations.

BD Pharmingen™ Purified Mouse Anti-Mouse CD157 - Purified - Clone BP-3 - Isotype Mouse IgG2b, κ - Reactivity Ms - 0.1 mg

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Immunogène: Mouse pre-B cell line

Clone: BP

Isotype: IgG2b kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store undiluted at 4°C.

Références pour anticorps anti-BST1 (ABIN2688997)

Ngo, Korner, Gunn, Schmidt, Riminton, Cooper, Browning, Sedgwick, Cyster: "Lymphotoxin alpha/beta and tumor necrosis factor are required for stromal cell expression of homing chemokines in B and T cell areas of the spleen." dans: The Journal of experimental medicine, Vol. 189, Issue 2, pp. 403-12, (1999) (PubMed).

Itoh, Ishihara, Hiroi, Lee, Maeda, Iijima, Yanagita, Kiyono, Hirano: "Deletion of bone marrow stromal cell antigen-1 (CD157) gene impaired systemic thymus independent-2 antigen-induced IgG3 and mucosal TD antigen-elicited IgA responses." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 161, Issue 8, pp. 3974-83, (1998) (PubMed).

Dong, Willerford, Alt, Cooper: "Genomic organization and chromosomal localization of the mouse Bp3 gene, a member of the CD38/ADP-ribosyl cyclase family." dans: Immunogenetics, Vol. 45, Issue 1, pp. 35-43, (1996) (PubMed).

Dong, Wang, Neame, Cooper: "The murine BP-3 gene encodes a relative of the CD38/NAD glycohydrolase family." dans: International immunology, Vol. 6, Issue 9, pp. 1353-60, (1995) (PubMed).

McNagny, Bucy, Cooper: "Reticular cells in peripheral lymphoid tissues express the phosphatidylinositol-linked BP-3 antigen." dans: European journal of immunology, Vol. 21, Issue 2, pp. 509-15, (1991) (PubMed).

McNagny, Cazenave, Cooper: "BP-3 alloantigen. A cell surface glycoprotein that marks early B lineage cells and mature myeloid lineage cells in mice." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 141, Issue 8, pp. 2551-6, (1988) (PubMed).

Détails sur BST1

Antigène: BST1 (Bone Marrow Stromal Cell Antigen 1 (BST1))

Autre désignation: CD157 (BST1 Produits)

Synonymes: anticorps BST1, anticorps 114/A10, anticorps A530073F09, anticorps BP-3, anticorps Bp3, anticorps Bsta1, anticorps CD157, anticorps Ly65, anticorps bone marrow stromal cell antigen 1, anticorps BST1, anticorps Bst1

Sujet: Synonyms: BP-3 Alloantigen