CD79a anticorps

N° du produit ABIN2689396

Cet anticorps anti-CD79a est un anticorps Souris Monoclonal détectant CD79a dans ICS. Adapté pour Humain et Souris. Ce Primary Antibody a été cité dans 2+ publications.

Aperçu rapide pour CD79a anticorps (ABIN2689396)

Antigène: CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD79a est non-conjugé

Application: Intracellular Staining (ICS)

Clone: HM47

Détail du produit anti-CD79a anticorps

Marque: BD Pharmingen™

Attributs du produit: Reacts with the cytoplasmic domain of a 47 kDa membrane glycoprotein present on B lymphocytes, also referred to as mb-1. It is expressed on B cells at various stages of differentiation, from pre-B cell stage, probably before expression of cytoplasmic μ chain, to plasma cell stage, in which it is detected only in the cytoplasm. CD79a associates with CD79b to form part of the B-cell receptor complex. It has been suggested that CD79a may play a role in mediating the transport of IgM to the cell surface. This antibody has been found to react on permeabilized A20 cells (mouse B cell line). Profile of permeabilized peripheral blood lymphocytes with Cytofix/Cytoperm (Cat# 554714) analyzed on a FACScan

BD Pharmingen™ Purified Mouse Anti-Human CD79a - Purified - Clone HM47 - Isotype Mouse IgG1, κ - Reactivity Hu, Ms - 0.1 mg

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store undiluted at 4°C.

Références pour anticorps anti-CD79a (ABIN2689396)

Mason, Cordell, Tse, van Dongen, van Noesel, Micklem, Pulford, Valensi, Comans-Bitter, Borst: "The IgM-associated protein mb-1 as a marker of normal and neoplastic B cells." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 147, Issue 11, pp. 2474-82, (1991) (PubMed).

Sakaguchi, Kashiwamura, Kimoto, Thalmann, Melchers: "B lymphocyte lineage-restricted expression of mb-1, a gene with CD3-like structural properties." dans: The EMBO journal, Vol. 7, Issue 11, pp. 3457-64, (1989) (PubMed).

Détails sur CD79a

Antigène: CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))

Autre désignation: CD79a

Sujet: Synonyms: Igα, mb-1

Pathways: BCR Signaling