IL-4 anticorps

N° du produit ABIN2689765

Cité dans 4 publications. Cet anticorps anti-IL-4 Monoclonal Souris (Clone OX) (ABIN2689765) détecte spécifiquement IL-4 dans ELISA, Neut et BR. L’anticorps est réactif avec des échantillons de Rat.

Aperçu rapide pour IL-4 anticorps (ABIN2689765)

Antigène: IL-4 (IL4) (Interleukin 4 (IL4))

Reactivité: Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IL-4 est non-conjugé

Application: ELISA, Neutralization (Neut), Blocking Reagent (BR)

Clone: OX

Détail du produit anti-IL-4 anticorps

Attributs du produit: The OX-81 antibody reacts with rat interleukin-4 (IL-4). The immunogen used to generate this hybridoma was recombinant rat IL-4 protein. This is a neutralizing antibody. This antibody is routinely tested by ELISA capture. Other applications were tested during antibody development only or reported in the literature. Rat IL-4 ELISA Standard Curve.

BD Pharmingen™ Purified Mouse Anti-Rat IL-4 - Purified - Clone OX-81 - Isotype Mouse IgG1, κ - Reactivity Rat - 0.5 mg

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Immunogène: Recombinant rat IL-4 protein

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store undiluted at 4°C.

Références pour anticorps anti-IL-4 (ABIN2689765)

Ramírez, Fowell, Puklavec, Simmonds, Mason: "Glucocorticoids promote a TH2 cytokine response by CD4+ T cells in vitro." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 156, Issue 7, pp. 2406-12, (1996) (PubMed).

Prussin, Metcalfe: "Detection of intracytoplasmic cytokine using flow cytometry and directly conjugated anti-cytokine antibodies." dans: Journal of immunological methods, Vol. 188, Issue 1, pp. 117-28, (1996) (PubMed).

Prigent, Saoudi, Pannetier, Graber, Bonnefoy, Druet, Hirsch: "Mercuric chloride, a chemical responsible for T helper cell (Th)2-mediated autoimmunity in brown Norway rats, directly triggers T cells to produce interleukin-4." dans: The Journal of clinical investigation, Vol. 96, Issue 3, pp. 1484-9, (1995) (PubMed).

Saoudi, Simmonds, Huitinga, Mason et al.: "Prevention of experimental allergic encephalomyelitis in rats by targeting autoantigen to B cells: evidence that the protective mechanism depends on changes in the cytokine response and migratory ..." dans: The Journal of experimental medicine, Vol. 182, Issue 2, pp. 335-44, (1995) (PubMed).

Détails sur IL-4

Antigène: IL-4 (IL4) (Interleukin 4 (IL4))

Autre désignation: IL-4

Pathways: Signalistation JAK/STAT, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport, Activated T Cell Proliferation