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Perforin 1 anticorps
PRF1
Reactivité: Humain, Boeuf (Vache)
WB, IP, IF, IHC (fro), IHC (f), ICS
Hôte: Souris
Monoclonal
deltaG9
unconjugated
N° du produit ABIN2689879
Détail du produit anti-Perforin 1 anticorps
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Antigène
Voir toutes Perforin 1 (PRF1) Anticorps
Perforin 1 (PRF1)
(Perforin 1 (Pore Forming Protein) (PRF1))
Reactivité
Toutes les réactivités sur Perforin 1 Anticorps
Humain, Boeuf (Vache)
Hôte
Toutes les hôtes sur Perforin 1 Anticorps
Souris
Clonalité
Toutes les clonalités sur Perforin 1 Anticorps
Monoclonal
Conjugué
Tous les conjugués à travers Perforin 1 Anticorps
Cet anticorp Perforin 1 est non-conjugé
Application
Tous les applications à travers Perforin 1 Anticorps.
Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Intracellular Staining (ICS)
Marque
BD Pharmingen™
Attributs du produit
Perforin has a key role in cell-mediated cytotoxicity. It is a 70 kDa cytolytic protein that is expressed in the cytoplasmic granules of cytotoxic T lymphocytes (CTLs) and natural killer (NK) cells. CTLs are involved in eliminating virally infected cells, in anti-tumor immune responses, in allograft rejections, and in some autoimmune diseases. NK cells are important for tumor surveillance and destruction and are involved in allograft rejections. Cytotoxic cells release the contents of their cytotoxic granules, including perforin upon recognition of their target cell. In the presence of calcium, perforin forms transmembrane channels or pores in the membrane of the target cell leading to a cell death that resembles apoptosis. The ability to detect perforin-positive cells with specific antibody should be useful in identifying and understanding perforin-mediated reactions. BD Pharmingen™ Purified Mouse Anti-Human Perforin - Purified - Clone δG9 - Isotype Mouse IgG2b, κ - Reactivity Hu, Cow - 0.1 mg
Purification
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Immunogène
Purified Granules from the Human Lymphoma Cell Line YT
Clone
DeltaG9
Isotype
IgG2b kappa
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Alternatives
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
(cache)
Concentration
0.5 mg/mL
Buffer
Aqueous buffered solution containing ≤0.09 % sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C
Stockage commentaire
Store undiluted at 4°C.
Détails sur Perforin 1
(cache)
Antigène
Perforin 1 (PRF1)
(Perforin 1 (Pore Forming Protein) (PRF1))
Autre désignation
Perforin (PRF1 Produits )
Synonymes
anticorps FLH2, anticorps HPLH2, anticorps P1, anticorps PFN1, anticorps PFP, anticorps PRF1, anticorps Pfn, anticorps Pfp, anticorps Prf-1, anticorps Cyta, anticorps RATCYTA, anticorps LOC443187, anticorps perforin, anticorps prf1, anticorps cytolysin, anticorps perforin-1, anticorps perforin-1-like, anticorps perforin 1, anticorps perforin 1 (pore forming protein), anticorps perforin, anticorps perforin 1 L homeolog, anticorps PRF1, anticorps Prf1, anticorps LOC443187, anticorps prf1, anticorps prf1.L
Sujet
Synonyms: PRF1, P1, PERF, PFN1, PFP, Perforin-1, Cytolysin, FLH2, HPLH2
Pathways
Apoptose , Caspase Cascade in Apoptosis
Vus récemment
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