RIT1 anticorps

N° du produit ABIN271808

L’anticorps anti-RIT1 Polyclonal Lapin est utilisé pour la détection de RIT1 dans des échantillons de Humain et Souris. Il a été validé pour WB.

Aperçu rapide pour RIT1 anticorps (ABIN271808)

Antigène: RIT1 (Ras-Like Without CAAX 1 (RIT1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RIT1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-RIT1 anticorps

Specificité: This antibody detects endogenous levels of ROC1 protein. (region surrounding Trp204)

Réactivité croisée (Details): Species reactivity (tested):Human and Mouse.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Pureté: > 95 % pure by SDS-PAGE

Information d'application

Indications d'application: ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: DO NOT FREEZE!

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur RIT1

Antigène: RIT1 (Ras-Like Without CAAX 1 (RIT1))

Autre désignation: RIT1

Sujet: ROC 1 and ROC 2 are the two highly conserved RING finger proteins that are homologous to APC 11, a subunit of the anaphase promoting complex(APC). ROC 1 and ROC 2 commonly interact with all cullins while APC 11 specifically interacts with APC 2, a cullin related APC subunit. ROC 1 and APC 11 immunocomplexes can catalyze isopeptide ligations to form polyubiquitin chains in an E1 and E2 dependent manner. ROC 1 is thought to play a unique role in the ubiquitination reaction by heterodimerizing with cullin 1 to catalyze ubiquitin polymerization.Synonyms: RIBB, RIT, ROC1, Ras-like protein expressed in many tissues, Ras-like without CAAX protein 1

Poids moléculaire: approx. 25 kDa

ID gène: 6016

NCBI Accession: NP_008843

UniProt: Q92963

Pathways: Neurotrophin Signaling Pathway