S100A1 anticorps
Aperçu rapide pour S100A1 anticorps (ABIN271809)
Antigène
Voir toutes S100A1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
- This antibody detects endogenous levels of S100A1 protein. (region surrounding Ala18)
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Réactivité croisée (Details)
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
Purification
- Affinity-Chromatography using epitope-specific immunogen
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Indications d'application
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ELISA: 1: 20000approx. 1: 40000WB: 1: 500approx. 1: 1000IHC: 1: 50approx. 1: 200IF: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer .
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- S100A1 (S100 Calcium Binding Protein A1 (S100A1))
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Autre désignation
- S100A1
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Sujet
- S100 calcium binding protein A1 (S100-alpha/ S100A1), it is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies.Synonyms: S-100 protein alpha chain, S-100 protein subunit alpha, S100 alpha, S100 calcium-binding protein A1, S100-A1, S100A
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Poids moléculaire
- approx. 10 kDa
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ID gène
- 6271
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NCBI Accession
- NP_006262
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UniProt
- P23297
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Pathways
- Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades, S100 Proteins
Antigène
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