beta Synuclein anticorps

N° du produit ABIN271836

Cet anticorps anti-beta Synuclein Polyclonal Lapin (ABIN271836) détecte spécifiquement beta Synuclein dans WB, IF et IHC (p). L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour beta Synuclein anticorps (ABIN271836)

Antigène: beta Synuclein (SNCB) (Synuclein, beta (SNCB))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp beta Synuclein est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-beta Synuclein anticorps

Specificité: This antibody detects endogenous levels of Synuclein beta protein. (region surrounding Ser118)

Réactivité croisée (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Pureté: > 95 % pure by SDS-PAGE

Information d'application

Indications d'application: ELISA: 1: 5000approx. 1: 10000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200. IF: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: DO NOT FREEZE!

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur beta Synuclein

Antigène: beta Synuclein (SNCB) (Synuclein, beta (SNCB))

Autre désignation: beta-Synuclein / SCNB

Sujet: The synuclein family members, including alpha-synuclein (also designated NACP for non-beta amyloid component) and beta-synuclein, are predominantly expressed in the brain and are speculated to be involved in synaptic regulation and neuronal plasticity. alpha-synuclein is localized to neuronal cell bodies and synapses. alpha-synuclein was first identified as a component of Alzheimers disease amyloid plaques. Abnormal platelet function in Alzheimers disease has been demonstrated. During megakaryocytic differentiation alpha-synuclein was found to be upregulated, while beta-synuclein is downregulated, indicating that coordinate expression of synucleins may be important during hematopoetic cell differentiation. A mutant form of alpha-synuclein has been found in patients with early onset Parkinsons disease.Synonyms: Synuclein beta

Poids moléculaire: approx. 14 kDa

ID gène: 6620

NCBI Accession: NP_001001502

UniProt: Q16143