CDK2 anticorps

N° du produit ABIN2718383

Détail du produit anti-CDK2 anticorps

Antigène: CDK2 (Cyclin-Dependent Kinase 2 (CDK2))

Reactivité: Humain, Singe

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CDK2 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF)

Attributs du produit: Homo sapiens cyclin-dependent kinase 2 (CDK2), transcript variant 1

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogène: Full length human recombinant protein of human CDK2 (NP_001789) produced in HEK293T cell.

Clone: 1C4

Isotype: IgG2a

Information d'application

Indications d'application: WB 1:500~2000, IF 1:100, FLOW 1:100

Commentaires:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur CDK2

Antigène: CDK2 (Cyclin-Dependent Kinase 2 (CDK2))

Autre désignation: CDK2 (CDK2 Produits)

Synonymes: anticorps p33(CDK2), anticorps A630093N05Rik, anticorps wu:fa10c02, anticorps zgc:56598, anticorps zgc:77684, anticorps eg1, anticorps CDKN2, anticorps cdk2L, anticorps cyclin dependent kinase 2, anticorps cyclin-dependent kinase 2, anticorps cyclin-dependent kinase 2 S homeolog, anticorps CDK2, anticorps Cdk2, anticorps cdk2, anticorps cdk2.S

Sujet: The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. This protein associates with and regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by its protein phosphorylation. Two alternatively spliced variants and multiple transcription initiation sites of this gene have been reported.

Poids moléculaire: 33.7 kDa

ID gène: 1017

NCBI Accession: NM_001798

HGNC: 1017

Pathways: Signalisation PI3K-Akt, Cycle Cellulaire, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA