CDKN2B anticorps

N° du produit ABIN2718414

Cet anticorps anti-CDKN2B Monoclonal Souris (Clone 3E4) (ABIN2718414) détecte spécifiquement CDKN2B dans WB et FACS. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour CDKN2B anticorps (ABIN2718414)

Antigène: CDKN2B (Cyclin-Dependent Kinase Inhibitor 2B (p15, Inhibits CDK4) (CDKN2B))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CDKN2B est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: 3E4

Détail du produit anti-CDKN2B anticorps

Attributs du produit: Homo sapiens cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) (CDKN2B), transcript variant 1

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogène: Full length human recombinant protein of human CDKN2B(NP_004927) produced in HEK293T cell.

Isotype: IgG1

Information d'application

Indications d'application: WB 1:2000, FLOW 1:100,

Commentaires:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur CDKN2B

Antigène: CDKN2B (Cyclin-Dependent Kinase Inhibitor 2B (p15, Inhibits CDK4) (CDKN2B))

Autre désignation: CDKN2B

Sujet: This gene lies adjacent to the tumor suppressor gene CDKN2A in a region that is frequently mutated and deleted in a wide variety of tumors. This gene encodes a cyclin-dependent kinase inhibitor, which forms a complex with CDK4 or CDK6, and prevents the activation of the CDK kinases, thus the encoded protein functions as a cell growth regulator that controls cell cycle G1 progression. The expression of this gene was found to be dramatically induced by TGF beta, which suggested its role in the TGF beta induced growth inhibition. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported.

Poids moléculaire: 14.5 kDa

ID gène: 1030

NCBI Accession: NM_004936

HGNC: 1030

Pathways: Cycle Cellulaire, Mitotic G1-G1/S Phases