CDKN2B anticorps
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- Antigène Voir toutes CDKN2B Anticorps
- CDKN2B (Cyclin-Dependent Kinase Inhibitor 2B (p15, Inhibits CDK4) (CDKN2B))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CDKN2B est non-conjugé
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Application
- Western Blotting (WB), Flow Cytometry (FACS)
- Attributs du produit
- Homo sapiens cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) (CDKN2B), transcript variant 1
- Purification
- Purified from mouse ascites fluids by affinity chromatography
- Immunogène
- Full length human recombinant protein of human CDKN2B(NP_004927) produced in HEK293T cell.
- Clone
- 3E4
- Isotype
- IgG1
- Top Product
- Discover our top product CDKN2B Anticorps primaire
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- Indications d'application
- WB 1:2000, FLOW 1:100,
- Commentaires
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The concentration of the product may vary between diferrent lots.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5-1.0 mg/mL
- Buffer
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
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- Antigène
- CDKN2B (Cyclin-Dependent Kinase Inhibitor 2B (p15, Inhibits CDK4) (CDKN2B))
- Autre désignation
- CDKN2B (CDKN2B Produits)
- Synonymes
- anticorps p14-INK4b, anticorps cdk4l, anticorps ink4b, anticorps mts2, anticorps p15, anticorps p15ink4b, anticorps tp15, anticorps CDK4I, anticorps INK4B, anticorps MTS2, anticorps P15, anticorps TP15, anticorps p15INK4b, anticorps AV083695, anticorps INK4b, anticorps p15(INK4b), anticorps CDKN2A, anticorps cyclin dependent kinase inhibitor 2B, anticorps Cyclin-dependent kinase 4 inhibitor B, anticorps cyclin-dependent kinase inhibitor 2B, anticorps cyclin-dependent kinase inhibitor 2B L homeolog, anticorps cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4), anticorps CDKN2B, anticorps cdn2b, anticorps cdkn2b, anticorps cdkn2b.L, anticorps Cdkn2b
- Sujet
- This gene lies adjacent to the tumor suppressor gene CDKN2A in a region that is frequently mutated and deleted in a wide variety of tumors. This gene encodes a cyclin-dependent kinase inhibitor, which forms a complex with CDK4 or CDK6, and prevents the activation of the CDK kinases, thus the encoded protein functions as a cell growth regulator that controls cell cycle G1 progression. The expression of this gene was found to be dramatically induced by TGF beta, which suggested its role in the TGF beta induced growth inhibition. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported.
- Poids moléculaire
- 14.5 kDa
- ID gène
- 1030
- NCBI Accession
- NM_004936
- HGNC
- 1030
- Pathways
- Cycle Cellulaire, Mitotic G1-G1/S Phases
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