Dynamin 1 anticorps
-
- Antigène Voir toutes Dynamin 1 (DNM1) Anticorps
- Dynamin 1 (DNM1)
-
Reactivité
- Humain, Souris, Rat
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp Dynamin 1 est non-conjugé
-
Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- Specificité
- This antibody detects endogenous levels of Dynamin-1 protein. (region surrounding Val768)
- Réactivité croisée (Details)
-
Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. - Purification
- Affinity Chromatography using epitope-specific immunogen.
- Top Product
- Discover our top product DNM1 Anticorps primaire
-
-
- Indications d'application
-
ELISA: 1:5000approx. 1:10000. WB: 1:500approx. 1:1000. IHC: 1:50approx. 1:200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
-
- Concentration
- 1.0 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH ~7.2 containing 0.05 % Sodium Azide as preservative.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
- Antigène
- Dynamin 1 (DNM1)
- Autre désignation
- Dynamin-1 (DNM1 Produits)
- Synonymes
- anticorps DNM, anticorps Dnm, anticorps AI838169, anticorps Ftfl, anticorps mKIAA4093, anticorps dnm, anticorps DNM1, anticorps Dnm1, anticorps dnm1, anticorps si:dkey-246l19.2, anticorps dynamin 1, anticorps dynamin-1, anticorps dynamin 1a, anticorps DNM1, anticorps Dnm1, anticorps BACOIKO008_37, anticorps PTRG_07818, anticorps PTRG_08097, anticorps dnm1, anticorps LOC100168088, anticorps LOC100199205, anticorps dnm1a
- Sujet
- Members of the Dynamin family, including Dynamin I and Dynamin II, are GTPase, microtubule-associated proteins which are involved in endocytosis, synaptic transmission and neurogenesis. Dynamin I is localized to the central nervous system, while Dynamin II exhibits ubiquitous distribution with highest expression in testis. Both Dynamin proteins contain SH3 and proline-rich domains that mediate interactions between the Dynamins and effectors of their GTPase activity. The interactions with these effectors, which include microtubules, acidic phospholipids and SH3 domain-containing proteins, are required for rapid endocytosis. Dynamin I appears to be recruited to Clathrin coated pits by SH3 domain interaction with Amphiphysin, a protein highly expressed in brain.Synonyms: DNM, DNM1
- Poids moléculaire
- approx. 98 kDa
- ID gène
- 1759
- NCBI Accession
- NP_001005336
- UniProt
- Q05193
- Pathways
- Toll-Like Receptors Cascades, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
-