Mammaglobin A anticorps
Aperçu rapide pour Mammaglobin A anticorps (ABIN271899)
Antigène
Voir toutes Mammaglobin A (SCGB2A2) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
- This antibody detects endogenous levels of Mammaglobin/SCGB2A2 protein. (region surrounding Phe66)
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Réactivité croisée (Details)
- Species reactivity (tested):Human and Rat.
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Purification
- Affinity Chromatography using epitope-specific immunogen.
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Indications d'application
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ELISA: 1/1000-1/5000. Western Blot: 1/500-1/1000. Immunohistochemistry: 1/50-1/200. Immunofluorescence: 1/50-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Mammaglobin A (SCGB2A2) (Secretoglobin, Family 2A, Member 2 (SCGB2A2))
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Sujet
- Secretoglobins (also called lipophilins or mammaglobins) are small secreted proteins of endocrine-responsive organs and mucosal epithelia that form multimeric complexes and correlate with the development of various human cancers. Lipophilin A and Lipophilin B are orthologs of prostatein (estramustine-binding protein), the major secretory glycoprotein of the rat ventral prostate gland. Lipophilin A, also designated LIPA, LPHA and secretoglobin,family 1D, member 1 (SCGB1D1), is a component of a heterodimeric molecule present in human tears. Lipophilin B, also designated LIPB, LPHB and secretoglobin,family 1D, member 2 (SCGB1D2), mRNA can be overexpressed in breast tumors and shows a high degree of correlation with the mRNA expression profile of mammaglobin. Histological detection in breast tissue of Mammaglobin A, also designated MGB1 and secretoglobin, family 2A, member 2 (SCGB2A2) and Mammaglobin B, also designated MGB2, Lipophilin C, LPHC, UGB3 and SCGB2A2, is a reliable diagnostic marker for breast tumors.Synonyms: MGB1, Mammaglobin-1, Mammaglobin-A, Prostatein peptide C3, Prostatic steroid-binding protein C3, Secretoglobin family 2A member 2, UGB2
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Poids moléculaire
- approx. 20 kDa
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ID gène
- 4250
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NCBI Accession
- NP_002402
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UniProt
- Q13296
Antigène
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