WASP anticorps
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- Antigène Voir toutes WASP (WAS) Anticorps
- WASP (WAS) (Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS))
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp WASP est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificité
- This antibody detects endogenous levels of WASP protein. (region surrounding Glu284)
- Réactivité croisée (Details)
- Species reactivity (tested):Human and Mouse.
- Purification
- Affinity Chromatography using epitope-specific immunogen.
- Top Product
- Discover our top product WAS Anticorps primaire
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- Indications d'application
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ELISA: 1/5000-1/10000. Western Blot: 1/500-1/1000. Immunohistochemistry on Paraffin Sections: 1/50-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % Sdium Azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Antigène
- WASP (WAS) (Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS))
- Autre désignation
- WAS / IMD2 (WAS Produits)
- Synonymes
- anticorps IMD2, anticorps SCNX, anticorps THC, anticorps THC1, anticorps WASP, anticorps U42471, anticorps WASp, anticorps Wasp, anticorps imd2, anticorps thc, anticorps thc1, anticorps was, anticorps wasp, anticorps wu:fk81c08, anticorps zgc:64164, anticorps Wiskott-Aldrich syndrome, anticorps neural Wiskott-Aldrich syndrome protein, anticorps wiskott-aldrich syndrome protein, anticorps Wiskott-Aldrich syndrome L homeolog, anticorps Wiskott-Aldrich syndrome (eczema-thrombocytopenia) b, anticorps WAS, anticorps LOC5578888, anticorps CpipJ_CPIJ006699, anticorps Was, anticorps was.L, anticorps wasb
- Sujet
- The Wiskott-Aldrich syndrome (WAS) is a disorder that results from a monogenic defect that has been mapped to the short arm of the X chromosome at Xp11.23. WAS is characterized by thrombocytopenia, eczema, defects in cell-mediated and humoral immunity and a propensity for lymphoproliferative disease. The gene that is mutated in the syndrome encodes a 53 kDa proline-rich protein of unknown function designated WAS protein (WASP). A clue to WASP function came from the observation that T cells from affected males had an irregular cellular morphology and a disarrayed cytoskeleton suggesting the involvement of WASP in cytoskeletal organization. Close examination of the WASP sequence revealed a putative Cdc42/Rac interacting domain, homologous with those found in PAK65 and ACK. Subsequent investigation has shown WASP to be a true downstream effector of Cdc42.Synonyms: WASp, Wiskott-Aldrich syndrome protein
- Poids moléculaire
- approx. 53 kDa
- ID gène
- 7454
- NCBI Accession
- NP_000368
- UniProt
- P42768
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