TPT1 anticorps

N° du produit ABIN272165

Détail du produit anti-TPT1 anticorps

Antigène: TPT1 (Tumor Protein, Translationally-Controlled 1 (TPT1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TPT1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody detects endogenous levels of HRF protein. (region surrounding Lys100)

Réactivité croisée (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Pureté: > 95 % pure by SDS-PAGE

Information d'application

Indications d'application: ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: DO NOT FREEZE!

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur TPT1

Antigène: TPT1 (Tumor Protein, Translationally-Controlled 1 (TPT1))

Autre désignation: TPT1 / TCTP (TPT1 Produits)

Synonymes: anticorps HRF, anticorps TCTP, anticorps p02, anticorps Trt, anticorps p21, anticorps p23, anticorps TPT1, anticorps TCT1, anticorps tctp, anticorps fa28a02, anticorps id:ibd2078, anticorps wu:fa28a02, anticorps PCHK23, anticorps hrf, anticorps MGC79720, anticorps Tpt1, anticorps translationally controlled tumor protein, anticorps CG4800, anticorps Dmel\\CG4800, anticorps dTCTP, anticorps Tctp, anticorps tumor protein, translationally-controlled 1, anticorps tumor protein, translationally-controlled 1 L homeolog, anticorps translationally-controlled tumor protein, anticorps translationally controlled tumor protein, anticorps translationally controlled tumor-like protein, anticorps Translationally controlled tumor protein, anticorps translationally-controlled tumor protein homolog, anticorps P23 tumor protein-like, anticorps TPT1, anticorps Tpt1, anticorps tpt1, anticorps tpt1.L, anticorps LOC711798, anticorps TCTP, anticorps LOC548038, anticorps Tctp, anticorps LOC108708523, anticorps LOC109404863, anticorps LOC105389397, anticorps LOC102577554

Sujet: Histamine is an inflammatory mediator that is ubiquitously expressed and has a broad range of pharmacologic effects. Specifically, it plays a role in the central nervous, gastrointestinal, respiratory and immune systems. Histamine release is mediated by the stimulation of mast cells and basophils. Histamine-releasing factor (HRF) is a cytokine-like molecule that causes the release of histamine, IL-4 and IL-13 from basophils as well as the secretion of IL-8 and a calcium response in eosinophils. HRF belongs to the translationally controlled tumor protein (TCTP) family and is detected as a protein of 21 kDa in mice and 23 kDa in human. It is expressed in several healthy and tumoral cells, including erythrocytes, hepatocytes, macrophages, platelets, keratinocytes, erythroleukemia cells, gliomas, melanomas, hepatoblastomas and lymphomas, and it is localized in the cytoplasm. HRF plays a pivotal role in allergic diseases, and due to its wide distribution in brain, is thought to be involved in neurodegenerative disorders, such as Alzheimer's disease and Down Syndrome.Synonyms: Fortilin, HRF, Histamine-releasing factor, Translationally-controlled tumor protein

Poids moléculaire: approx. 24 kDa

ID gène: 7178

NCBI Accession: NP_003286

UniProt: P13693

Pathways: Response to Water Deprivation, Regulation of Cell Size, Negative Regulation of intrinsic apoptotic Signaling