SRY anticorps

N° du produit ABIN272215

Détail du produit anti-SRY anticorps

Antigène: SRY (Sex Determining Region Y (SRY))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SRY est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody detects endogenous levels of SRY protein. (region surrounding Leu80)

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Pureté: > 95 % pure by SDS-PAGE

Information d'application

Indications d'application: ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: DO NOT FREEZE!

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur SRY

Antigène: SRY (Sex Determining Region Y (SRY))

Autre désignation: SRY / TDF (SRY Produits)

Synonymes: anticorps SRXX1, anticorps SRXY1, anticorps TDF, anticorps TDY, anticorps SRYGENE, anticorps Sry1, anticorps Sry3BI, anticorps Tdf, anticorps Tdy, anticorps SRY, anticorps sex determining region Y, anticorps sex determining region of Chr Y, anticorps SRY, anticorps Sry

Sujet: SRY (sex-determining region Y protein) is a transcriptional activator required for male sex determination in mammals. This protein, also referred to as testis-determining factor (TDF), is an HMG box protein that initiates the formation of testis from undifferentiated gonad. The DNA-binding activity of SRY is required for normal testis formation. This DNA-binding activity is thought to be regulated by PKA, which phosphorylates SRY in vivo. Mutations in SRY have been associated with 46,XY gonadal dysgenesis, in which the gonads fail to develop in XY phenotypic females.Synonyms: Sex-determining region Y protein, Testis-determining factor

Poids moléculaire: approx. 37 kDa

ID gène: 100130809

NCBI Accession: NP_003131

UniProt: Q05066