E2F2 anticorps
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- Antigène Voir toutes E2F2 Anticorps
- E2F2 (E2F Transcription Factor 2 (E2F2))
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp E2F2 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificité
- This antibody detects endogenous levels of E2F-2 protein. (region surrounding Lys236)
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
- Pureté
- > 95 % pure by SDS-PAGE
- Top Product
- Discover our top product E2F2 Anticorps primaire
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- Indications d'application
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ELISA: 1: 5000approx. 1: 10000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1,0 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- DO NOT FREEZE!
- Stock
- 4 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C.
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- Antigène
- E2F2 (E2F Transcription Factor 2 (E2F2))
- Autre désignation
- E2F2 (E2F2 Produits)
- Synonymes
- anticorps E2F-2, anticorps CG1071, anticorps Dmel\\CG1071, anticorps E2F, anticorps E2F2, anticorps dE2F-2, anticorps dE2F2, anticorps dE2f2, anticorps de2f2, anticorps e2f2, anticorps 9230110J10, anticorps E130207A07, anticorps fb40b03, anticorps wu:fb40b03, anticorps E2F transcription factor 2, anticorps si:ch211-160f23.5, anticorps E2F2, anticorps E2f2, anticorps si:ch211-160f23.5
- Sujet
- The human retinoblastoma gene product appears to play an important role in the negative regulation of cell proliferation. Functional inactivation of Rb can be mediated either through mutation or as a consequence of interaction with DNA tumor virus-encoded proteins. Of all the Rb associations described to date, the identification of a complex between Rb and the transcription factor E2F most directly implicates Rb in regulation of cell proliferation. E2F was originally identified through its role in transcriptional activation of the adenovirus E2 promoter. Sequences homologous to the E2F binding site have been found upstream of a number of genes that encode proteins with putative functions in the G1 and S phases of the cell cycle. E2F-1 is a member of a broader family of transcription regulators including E2F-2, E2F-3, E2F-4, E2F-5 and E2F-6, each of which forms heterodimers with a second protein, DP-1, forming an active E2F transcriptional regulatory complex.Synonyms: E2F transcription factor 2, E2F-2, Transcription factor E2F2
- Poids moléculaire
- approx. 48 kDa
- ID gène
- 1870
- NCBI Accession
- NP_004082
- UniProt
- Q14209
- Pathways
- Cycle Cellulaire, Mitotic G1-G1/S Phases, DNA Replication
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