EPH Receptor A7 anticorps

N° du produit ABIN272234

L’anticorps anti-EPH Receptor A7 Polyclonal Lapin est utilisé pour la détection de EPH Receptor A7 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB.

Aperçu rapide pour EPH Receptor A7 anticorps (ABIN272234)

Antigène: EPH Receptor A7 (EPHA7)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EPH Receptor A7 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-EPH Receptor A7 anticorps

Specificité: This antibody detects endogenous levels of EphA7 protein. (region surrounding Glu477)

Réactivité croisée (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: Affinity Chromatography using epitope-specific immunogen.

Information d'application

Indications d'application: ELISA: 1/40000-1/60000. Western Blot: 1/500-1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur EPH Receptor A7

Antigène: EPH Receptor A7 (EPHA7)

Autre désignation: EPHA7

Sujet: The Eph subfamily represents the largest group of receptor protein tyrosine kinases identified to date. The Eph subfamily receptors of human origin (and their murine/avian homologs) include EphA1 (Eph), EphA2 (Eck), EphA3 (Hek4), EphA4 (Hek8), EphA5 (Hek7), EphA6 (Hek12), EphA7 (Hek11/MDK1), EphA8(Hek3), EphB1 (Hek6), EphB2 (Hek5), EphB3 (Cek10, Hek2), EphB4 (Htk), EphB5(Hek9) and EphB6 (Mep). EphAs are a family of receptor tyrosine kinases that are involved in axonal guidance during development. These receptors and their ligands, the ephrins, act via repulsive mechanisms to guide growing axons towards their appropriate targets and allow for the correct developmental connections to be made. Ligand binding to an Eph receptor results in tyrosine phosphorylation of the kinase domain, and repulsion of axonal growth cones and migrating cells. During neurulation, ephrin-A5 is coexpressed with its cognate receptor EphA7 in cells at the edges of the dorsal neural folds. Three different EphA7 splice variants, a full-length form and two truncated versions lacking kinase domains, are expressed in the neural folds.Synonyms: EHK3, EPH homology kinase 3, Ephrin type-A receptor 7, HEK11, Receptor protein-tyrosine kinase HEK11, Tyrosine-protein kinase receptor EHK-3

Poids moléculaire: approx. 112 kDa

ID gène: 2045

NCBI Accession: NP_004431

UniProt: Q15375

Pathways: Signalisation RTK