MKNK1 anticorps

N° du produit ABIN272252

Détail du produit anti-MKNK1 anticorps

Antigène: MKNK1 (MAP Kinase Interacting serine/threonine Kinase 1 (MKNK1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MKNK1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody detects endogenous levels of Mnk1 protein. (region surrounding Ile136)

Réactivité croisée (Details): Species reactivity (tested):Human, Mouse.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Pureté: > 95 % pure by SDS-PAGE

Information d'application

Indications d'application: ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: DO NOT FREEZE!

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur MKNK1

Antigène: MKNK1 (MAP Kinase Interacting serine/threonine Kinase 1 (MKNK1))

Autre désignation: MKNK1 (MKNK1 Produits)

Synonymes: anticorps MNK1, anticorps MKNK1, anticorps zgc:171912, anticorps 2410048M24Rik, anticorps Mnk1, anticorps MAPK signal-integrating kinase 1, anticorps mknk1, anticorps mnk1, anticorps MAP kinase interacting serine/threonine kinase 1, anticorps MAP kinase-interacting serine/threonine kinase 1, anticorps MAP kinase interacting serine/threonine kinase 1 S homeolog, anticorps MKNK1, anticorps mknk1, anticorps Mknk1, anticorps mknk1.S

Sujet: The MAPKAP kinases (for MAP kinase activated protein kinases) are a group of MAP kinase substrates which are themselves kinases. In response to activation, the MAP kinases phosphorylate downstream components on a consensus Pro-X-Ser/Thr-Pro motif. Several kinases that contain this motif have been identifed and serve as substrates for the ERK and p38 MAP kinases. These include the serine/threonine kinases Rsk-1 (also designated MAPKAP kinase-1), Rsk-2 and Rsk-3, which are phosphorylated by ERK1 and ERK2. Similarly p38 phosphorylates and activates the serine/threonine kinases MAPKAP kinase-2 and MAPKAP kinase-3 (also designated 3pK). The serine/threonine kinases Mnk1 and Mnk2 are substrates for both ERK and p38 MAP kinases.Synonyms: MAP kinase-interacting serine/threonine-protein kinase 1, MNK1

Poids moléculaire: approx. 51 kDa

ID gène: 8569

NCBI Accession: NP_001129025

UniProt: Q9BUB5

Pathways: Signalisation MAPK, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor