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YWHAE anticorps

YWHAE Reactivité: Humain, Souris, Rat WB, IF, IHC (p), EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN272265
  • Antigène Voir toutes YWHAE Anticorps
    YWHAE (14-3-3 epsilon (YWHAE))
    Reactivité
    • 51
    • 37
    • 33
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Humain, Souris, Rat
    Hôte
    • 48
    • 4
    • 1
    Lapin
    Clonalité
    • 41
    • 12
    Polyclonal
    Conjugué
    • 28
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp YWHAE est non-conjugé
    Application
    • 41
    • 17
    • 13
    • 13
    • 12
    • 10
    • 7
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificité
    This antibody detects endogenous levels of 14-3-3 ε protein. (region surrounding Asp238)
    Réactivité croisée (Details)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    Purification
    Affinity Chromatography using epitope-specific immunogen
    Top Product
    Discover our top product YWHAE Anticorps primaire
  • Indications d'application
    ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8° for one month or (in aliquots) at -20 °C for longer.
  • Hu, Sun, Li, Wang, Cai, Li, Zhao: "In Ovo injection of betaine affects hepatic cholesterol metabolism through epigenetic gene regulation in newly hatched chicks." dans: PLoS ONE, Vol. 10, Issue 4, pp. e0122643, (2016) (PubMed).

    Nagappan, Park, Park, Hong, Yumnam, Lee, Kim, Kim, Lee, Lee, Cho, Lee, Won, Cho, Kim: "Helicobacter pylori infection combined with DENA revealed altered expression of p53 and 14-3-3 isoforms in Gulo-/- mice." dans: Chemico-biological interactions, Vol. 206, Issue 2, pp. 143-52, (2013) (PubMed).

  • Antigène
    YWHAE (14-3-3 epsilon (YWHAE))
    Autre désignation
    14-3-3 Protein epsilon (YWHAE Produits)
    Synonymes
    anticorps 14-3-3, anticorps 14-3-3 epsilon, anticorps 14-3-3-e, anticorps 14-3-3-epsilon, anticorps 14-3-30epsilon, anticorps 14-3-3EPSILON, anticorps 14-3-3e, anticorps 14-3-3omicron, anticorps 1433epsilon, anticorps 143E_DROME, anticorps CG31196, anticorps CT24092, anticorps D14-3-3e, anticorps D14-3-3epsilon, anticorps Dmel\\CG31196, anticorps EK3-5, anticorps PAR-5, anticorps PAR5, anticorps Par-5, anticorps SR3-9, anticorps Su(Raf)3B, anticorps anon-WO0172774.141, anticorps anon-WO02059370.52, anticorps d14-3-3epsilon, anticorps eps, anticorps l(3)j2B10, anticorps par-5, anticorps 14-3-3epsilon, anticorps kcip-1, anticorps mdcr, anticorps mds, anticorps LOC581376, anticorps Ywhae, anticorps ACYPI002517, anticorps YWHAE, anticorps 14-3-3E, anticorps KCIP-1, anticorps MDCR, anticorps MDS, anticorps AU019196, anticorps fe38c12, anticorps wu:fb48f06, anticorps wu:fe38c12, anticorps wu:fi22e10, anticorps ywhae, anticorps zgc:55377, anticorps zgc:77062, anticorps CG31196 gene product from transcript CG31196-RD, anticorps tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon, anticorps 14-3-3 epsilon, anticorps 14-3-3 epsilon protein, anticorps 14-3-3 protein epsilon, anticorps tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide, anticorps tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon, anticorps tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon S homeolog, anticorps tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 1, anticorps 14-3-3epsilon, anticorps ywhae, anticorps LOC581376, anticorps Ywhae, anticorps HCAG_04173, anticorps PTRG_02836, anticorps PTRG_04459, anticorps UREG_07864, anticorps YWHAE, anticorps ywhae.S, anticorps ywhae1
    Sujet
    14-3-3 proteins regulate many cellular processes relevant to cancer biology, notably apoptosis, mitogenic signaling and cell-cycle checkpoints. Seven isoforms comprise this family of signaling intermediates, denoted 14-3-3 β, γ, ε, ζ, η, θ and σ. 14-3-3 proteins form dimers that present two binding sites for ligand proteins, thereby bringing together two proteins that may not otherwise associate. These ligands largely share a 14-3-3 consensus binding motif and exhibit serine/threonine phosphorylation. 14-3-3 proteins function in broad regulation of these ligand proteins, by cytoplasmic sequestration, occupation of interaction domains and import/export sequences, prevention of degradation, activation/repression of enzymatic activity and facilitation of protein modification, and thus loss of expression contributes to a vast array of pathogenic cellular activities.Synonyms: 14-3-3E, YWHAE
    Poids moléculaire
    approx. 29 kDa
    ID gène
    7531
    NCBI Accession
    NP_006752
    UniProt
    P62258
    Pathways
    Neurotrophin Signaling Pathway, Myometrial Relaxation and Contraction, M Phase
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